Motivation, lack

Basic causes related to personal factors Inadequate information inadequate experience excessive work pressure inadequate motivation lack of rest inadequate training reluctance to ask. 

Supervisors are responsible to see that every worker is adequate on the job. Physically, mentally, and emotionally inadequate workers are accident prone. Personal hazards are lack of knowledge, conflict of motives, physical, and mental factors. 

Avoid nuisance noise Provide adequate ventilation Avoid high uniform temperatures Avoid lack of air movement Provide adequate humidity Avoid uniform dull lighting and decor Provide natural lighting avoid tinted glass Ensure staff are motivated... 

The immediate cause of the explosion was an operator forgetting to open a valve. It was not due to lack of knowledge, training, or instructions but was another of those slips that even well-trained, well-motivated, capable people make from time to time. 

The traditional safety engineering approach to accident causation focuses on the individual rather than the system causes of error. Errors are primarily seen as being due to causes such as lack of motivation to behave safely, lack of discipline or lack of knowledge of what constitutes safe behavior. These are assumed to give rise to "unsafe acts." These unsafe acts, in combination with "unsafe situations" (e.g., imguarded plant, toxic substances) are seen as the major causes of accidents. 

In higher eukaiyotes, most of the chromosomal DNA carries 5-methyl-cytidine residues located in CpG sequence motives. There is a close correlation between transcriptional inactivation and methylation. On the other hand, considerable evidence shows that regions of DNA that are actively engaged in transcription lack 5-methyl-cytidine nucleotides in CpG motivs. Hence DNA methylation is a means how cells regulate gene expression. DNA methylation which is catalyzed by DNA methyltransferases is the best characterized epigenetic mechanism. 

Low standards of water treatment and waterside chemistry are generally caused by a combination of bad advice and lack of operator motivation or resources, and provide an initiator for the onset of downstream waterside operational problems. However, despite these apparent water treatment imperfections, most operators somehow still manage to function and produce steam of an acceptable quality and quantity, year after year ... 

There is a substantial weight of evidence for the cytoskeleton being responsible for the force production and control of cell locomotion. This view has not yet been accepted unanimously. However, an alternative hypothesis continues to be argued which states that membrane cycling is the motive force driving cell locomotion (Bretscher, 1987). One of the predictions of the membrane flow hypothesis is that there should be a discernible flow of lipid from the front to the rear of the cell. Lipid flow has proven very difficult to study, because of the lack of suitable methods to label single lipid molecules and the heterogenous behavior of membrane-associated proteins. The observation that particles were transported rearward when they bound... 

A strong focus on estimating external costs from chemicals is motivated since there has been a severe lack of information and knowledge in this area, but the external costs must be complemented with benefit assessment in order for a CB A to provide a useful result. An external cost estimate only provides partial results and should not be used as policy support in itself. 

The success of the initial PONDRs based on small databases of disordered protein motivated attempts to improve predictor accuracy. The main limitation for such attempts has been and continues to be the lack of low-noise structural data for both ordered and disordered protein, where noise means ordered regions misclassified as disordered and vice versa. 

After the acute psychotic episode has resolved, the patient typically has residual features (e.g., anxiety, suspiciousness, lack of volition, lack of motivation, poor insight, impaired judgment, social withdrawal, difficulty in learning from experience, and poor self-care skills). Patients often have comorbid substance abuse and are nonadherent with medications. 

Triple reuptake inhibitors (TRIs), which inhibit reuptake at all three transporters, have attracted considerable interest in recent years [77]. The involvement of dopamine reuptake in the etiology of depression and other CNS disorders has been recognized [29,30]. As a result, TRIs have been proposed to offer a faster onset of action and improved efficacy for depression over currently prescribed single or dual action monoamine reuptake inhibitors. Historically, the mesocorticolimbic dopamine pathway is thought to mediate the anhedonia and lack of motivation observed in depressed patients [78,79]. In addition, methylphenidate, both immediate release and extended release formula, has been found to be effective as an augmenting agent in treatment-resistant depression [4]. Furthermore, clinical studies using the combination of bupropion and an SSRI or SNRI have showed improved efficacy for the treatment of MDD in patients refractory to the treatment with SSRIs, SNRIs, or bupropion alone [5,80,81]. 

Another assumption that we professionals sometimes make is that we should be able to help our clients get better, when the reality is that they must help themselves. We can show them the door, but ultimately it is the clients who must walk through it to better health. When a person does not walk through the door, it is easy to personalize our responsibility for the lack of progress and get frustrated because we could not help him or her. Long-term frustration in working with clients can lead to apathy or disillusionment, stepping stones toward what some have called professional burnout. In my opinion, burnout occurs as a result of unrealistic expectations by professionals about their own abilities to help others and of unrealistic expectations for their clients to get better. The truth is that behavior change is completely up to the client. We can motivate and teach but we cannot force people to act. 

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