Moniliformin

Note The reagent can be employed on silica gel, kieselguhr, cellulose and polyamide layers. When left exposed to air the whole chromatogram is slowly colored blue because of the formation of the blue cation (3) (see Reaction). The detection limits for patulin, moniliformine and penicillic acid are ca. 50 ng per chromatogram zone. 

Cyc1oadditiORE between chloroketcnes and electron-rich double bonds occur very easily. The microbial toxin moniliformin (10) has been made using this reaction,... 

Fusarium species Trichothecenes Zearalenone Fumonisins Moniliformin... 

Deoxynivalenol Nivalenol Zearalenone T-2 toxin Moniliformin Ochratoxin A Aflatoxins... 

Fumonisins, fusaric RAPD marker PCR acid, fusarin C, moniliformin, naphdioquinone pigments, beauvericin... 

Fumonisins, beauvericin, moniliformin, naphthoquinone pigments, fusaric acid, fusarin C, gibebyrones see fumonisin producers... 

Kristensen, R., Berdal, K. G., and Holst-Jensen, A. (2006a). Simultaneous detection and identification of trichothecene- and moniliformin-producing Fusarium species based on multiplex SNP analysis. /. Appl. Microbiol, pp. 11. doi 10.1111/j.l365-2672.2006.03166.x. 

A number of emerging methods such as fluorescence polarization immunoassays, dipsticks, or even newer methods such as biosensors have been used for rapid screening of mycotoxin (ochratoxin A and Fusarium toxins—funionisms (FBs), moniliformin (MON), zearalenone (ZON), and type-A and -B trichothecenes in foods, fodders, blood, urea, and tissues of pigs after slaughter) (Curtui et al. 2001 Krska et al., 2007). 

Chemical structure of moniliformin, toxin isolated from Fusarium moniliforme Sheldon. 

The point arose as to the actual site of action of moniliformin in plants. Earlier, it had been stated that the geometrical criteria of hydrogen bond formation suggested that MH could be regarded as either a purine or pyrimidine analogue and, therefore, could substitute as one of the base pairs in nucleic acid.11 And the fact that it had shown plant growth regulatory activity had led an industrial company to become interested in the product as a potential herbicide. 

Several derivatives of moniliformin were synthesized and patented. Swiss patent 609,836 was awarded to Fischer and Bellus (Ciba Geigy) in 1979. The cyclobutene-3, 4-diones, R-alkyl, substituted Ph, CH2CH2SEt, CH2CH CH2, etc. are herbicides and PGR s. Thus postemergence application of 4Kg 1-octyloxycyclobutene-3, 4-dione/ha controlled Setaria italica, Lolium perenne, Sinapis alba and Stellaria media more than did the standard moniliformin Na salt" (Chem. Abstracts. Vol 90 1979, Indent 90 1988 82p). 

Burmeister, H. R., Cieglar, A., and Vesonder, R. F. 1979. Moniliformin, a metabolite of Fusarium moniliforme NRRL 6322 purification and toxicity. Appl. Environ. Microbiol. 37, 11-13... 

Thiel, P. G. 1978. A molecular mechanism for the toxic action of moniliformin, a mycotoxin produced by Fusarium moniliforme. Biochem. Pharmacol. 15, 483-486... 

Various soilbome fungi have been reported to produce phytotoxins, some of which are listed in Table III. Certain phytotoxic compoimds are known to have pronounced n cotoxic activity (eg. moniliformin). Ve have excluded those fungi which have the potential to colonize edible parts of crops and produce mycotoxic... 

Moniliformin F. verticillioides neurotoxin cardiovascular lesion onyalai disease... 

Burka LT, Doran J, Wilson BJ. Enzyme inhibition and the toxic action of moniliformin and other vinylogous alpha-ketoacids. Biochem. Pharmacol. 1982 31 79-84. 

C4H203 moniliformin 31876-38-7 25.00 1 3644 2 2628 C4H5Br02 3-bromo-2-methyl-2-propenoic acid 89123-63-7 25.00 1.6561 2... 

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