Minty

Many cycHc ketones occur in natural oils. Jasmone [488-10-8] (3-meth5l-2-(2-pentyl)-2-cyclopenten-l-one) (4) is an odoriferous component of the oil obtained from jasmine flowers. /-Menthone [14073-97-3] (5) is the most frequently occurring of four optically active isomers, and is a colorless Hquid with a minty odor obtained from Mentha species of plants. Muscone [541-91-3] (6) and civetone [542-46-1] (7) are expensive animal products. 

The spreading of smells through still air is due to the diffusion of the gas molecules. In a room that is 5 m long, a vial of ethyl octanoate is opened at the north end of the room, and simultaneously a second vial containing p-anisaldehyde is opened at the south end of the room (5 m away). Ethyl octanoate (C10H20O2) has a fruity smell, and p-anisaldehyde (CgHsO,) has a minty smell. How far (in meters) from the north end of the room must a person stand to smell first a minty smell ... 

The 2-mg gum is recommended for those smoking less than 25 cigarettes a day, and the 4-mg gum for those smoking more than 25 cigarettes a day. Generally, the gum should be used for up to 12 weeks at doses of no more than 24 pieces per day. It should be chewed slowly until a peppery or minty taste emerges and then parked for about 30 minutes or until the taste dissipates. A fixed schedule may be more efficacious than as-needed use. 

Jones JG, Minty BD, Lawler P, Hulands G, Crawley JC, Veall N (1980) Increased alveolar epithelial permeability in cigarette smokers. Lancet 1 66-68. 

Laoukili J, Ferret E, Willems T, Minty A, Parthoens E, Houcine 0, Coste A, Jorissen M, Marano F, Caput D, Toumier F IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial ceUs. J Clin Invest 2001 108 1817-1824. 

The major constituent of caraway oil is (+)-carvone, and the typical caraway odour is mainly due to this component. On the other hand, the typical minty smell of spearmint oil is due to its major component, (—)-carvone. These enantiomers are unusual in having quite different smells, i.e. they interact with nasal receptors quite differently. The two enantiomeric forms are shown here in their half-chair conformations. 

Emberger and ITopp and Werkhoff and ITopp reported that there are significant sensory differences between the eight menthol and the four menthone enantiomers. (5)(-)-7-Hydroxy-6, 7-dihydrocitronellal has a lily-of-the-valley odor, while the odor of its enantiomer is weaker and has green, leaf like and minty notes.The enantiomers of cis- and trans-Tose oxide have closely similar odors with slight but detectable quality differences. ... 

Piperitone, with its fresh minty camphor4ike odor, is present in various leaf essential oils. Among Mentha and Eucalyptus genera, there are piperi tone-rich species which are considered common sources of this natural monoterpene ketone. The (45) (-f)- enantiomer was reported to be... 

Pelosi P, Viti R, Specific anosmia to 1-carvone The minty primary odour, Chem... 

Green fragrance of rose, lighty minty, less fresh than that of (S)- isomer... 

Gedanken A, Reisfeld R, Sominski E, Palchik O, Kolturin Yu, Panczer G, Gaft M, Minti H (2000) J Phys Chem B 104 7057-7065 Geschwind S, Kisluk P, Klein M, Remeika J, Wood D (1962) Phys Rev 126 1684-1686... 

Tyrer, S.P., Peat, M.A., Minty, P.S., Luchini, A., Glud, V., and Am-disen, A. (1982) Bioavailability of lithium carbonate and lithium citrate a comparison of two controlled-release preparations. Pharmatherapeutica 3 243-246. 

E Lifshitz, I Dag, I Litvin, G Hodes, S Gorer, R Reisfeld, M Zelner, H Minti. Chem. Phys. Lett. 188, 1998. 

Menthol from Cornmint Oil. Mentha arvensis oils, which may contain 70-80% free (—)-menthol, are cooled and the crystals separated by centrifugation. Since the crystalline product contains traces of cornmint oil, this menthol has a slightly herbaceous-minty note. Pure (—)-menthol is obtained by recrystallization from solvents with low boiling points. 

Both stereoisomers occur in many essential oils, often as a single enantiomer species. A particularly high concentration (sometimes >50%) is found in oils from Mentha species. The menthones are colorless liquids that possess a typically minty odor the odor of isomenthone is slightly musty. They have a strong tendency to interconvert and are, therefore, difficult to obtain in high purity. Industrial products are mixtures of varying composition. Physical constants of industrially important menthone isomers are listed in Table 1. 

Due to its characteristic penetrating, slightly minty odor, camphor is only used in perfuming industrial products. It is far more important as a plasticizer. 

A dehydrated linalool oxide, 2-methyl-2-vinyl-5-isopropenyltetrahydrofuran [13679-86-2], occurs naturally it has a minty eucalyptol odor and is used in perfumery. 

Buchu leaf oils are obtained by steam distillation of Barosma betulina (Bergius) Bartl. and Wendl. and B. crenulata (L.) Hook. (Rutaceae) leaves. The oils are dark yellow to brown liquids with a characteristic minty-fruity odor, reminiscent of blackcurrant. 

The residual dementholized oil is a colorless to yellow liquid with a characteristic minty odor typical specifications are given in Table 5 [622],... 

Spearmint oils are obtained by steam distillation of the flowering herbs of Mentha spicata L. (native spearmint) and Mentha cardiaca Ger. (Scotch spearmint). They are colorless to yellow-green liquids with a fresh, caraway-minty odor. 

Minti H, Eyal M, Reisfeld R, Berkovic G (1991) Chem Phys Lett 183 277... 

Y, stand for the odour similarity i = 1-ethereal, 2-camphoraceous, 3-musky, 4-floral, 5-minty)... 

A. P. Jucys and A. A. Bandzaitis. The Theory of Angular Momentum in Quantum Mechanics, Mintis Publishers, Vilnius, 1965 (in Russian, second extended edition in 1977). 

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