Migrations neuronal

Gleeson JG, Lin PT, Flanagan LA, Walsh CA 1999 Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 23 257—271 Goldstein B, Hird SN 1996 Specification of the anteroposterior axis in Caenorhabditit elegant. Development 122 1467-1474... 

Immunostaining for BrdU and markers for immature migrating neurons (PSA-NCAM, /3111-tubulin or Doublecortin) in frontal white matter did not reveal chains... 

Anton ES, Marchionni MA, Lee KF, Rakic P. 1997. Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex. Development 124 3501-3510. 

Rio C, Rieff HI, Qi P, Khurana TS, Corfas G. 1997. Neuregulin and erbB receptors play a critical role in neuronal migration. Neuron 19 39-50. 

Choi, B. H. and Lapham, L. W. (1974) Autoradiographic studies of migrating neurons and astrocytes of human fetal cerebral cortex in vitro. Eyp. Mol. Pathol. 21, 204-217. 

Several studies have determined that KSPGs may act as barriers to migrating neuronal growth cones during normal development of the central and peripheral ner-... 

Reelin is an extracellular matrix protein, which is secreted by neuronal cells and binds to two lipoprotein receptors (VLDLR and ApoER2) that relay the Reelin signal inside target neurons by docking the tyrosine kinase adapter disabled-1 (Dabl). This allows neurons to complete migration and adopt their ultimate positions in laminar structures in the central nervous system. In... 

Fak (focal adhesion kinase) is expressed in most tissues and is evolutionary conserved across species. It is activated by integrin clustering and by stimulation of several G protein-coupled recqrtors and RTKs. Fak is associated with focal adhesions and regulates cell spreading and migration. The kinase is essential for embryonic development since the homozygote Fak knockout is embryonic lethal. Pyk2 (proline-rich tyrosine kinase 2), the second member of the Fak kinase family has a more restricted expression pattern (primarily neuronal and hematopoietic cells) and does not localize to focal adhesions. 

The members of Group 1 are called the alkali metals. The chemical properties of these elements are unique and strikingly similar from one to another. Nevertheless, there are differences, and the subtlety of some of these differences is the basis of the most subtle property of matter consciousness. Our thinking, which relies on the transmission of signals along neurons, is achieved by the concerted action of sodium and potassium ions and their carefully regulated migration across membranes. So, even to learn about sodium and potassium, we have to make use of them in our brains. 

Cell migration and cytoplasmic movement involve predominantly actin filaments in the locomotion of neutrophilic granulocytes, both actin filaments and microtubules in the elongation of neuronal growth cones and migration of neurites, and both actin and myosin in cytokinesis and the contraction of skeletal and cardiac muscle. 

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