Microwave-induced plasma mass spectrometry

Huang M, Hirabayashi A, Shirasaki T, Koiznmi H (2000) A multimicrospray nebulizer for microwave-induced plasma mass spectrometry. Anal Chem 72 2463-2467 Ivanovich M, Murray A (1992) Spectroscopic methods. In Uranium-Series Disequilibrium Applications to Earth, Marine, and Enviromnental Sciences, 2" Ed. Ivanovich M, Harmon RS (eds) Orfbrd Univ. Press, Oxford... 

Story WC, Caruso JA. 1993. Gas chromatographic determination of phosphorus, sulfur and halogens using a water-cooled torch with reduced-pressure helium microwave-induced plasma mass spectrometry. J Anal Atomic Spectrometry 8 571-575. 

Suyani, H., Creed, J., Caruso, J. and Satzger, R.D. (1989) Helium microwave-induced plasma mass spectrometry for capillary gas chromatographic detection speciation of organotin compounds./. Anal. At. Spectrom., 4, 777-782. 

Yoshinaga and Morita used isotope dilution in conjunction with ICP-MS to measure mercury in biological and environmental samples [45]. The same group used microwave-induced plasma mass spectrometry for the isotope dilution analysis of selenium in biological materials [46]. Analysis of nickel via isotope dilution and ICP-MS has been reported by Patriarca et al [47]. 

Figure 2 Schematic diagram of a typical microwave induced plasma mass spectrometry (MIP-MS) instrument.

Microwave induced plasma mass spectrometry has also been used as a detector for supercritical fluid chromatography (SFC) [113] for the separation of halogenated hydrocarbons. The design of an SFC-MIP interface must ensure that the frit restrictor temperature remains at a high temperature to prevent condensation of analytes. Stainless steel transfer lines may be used. The frit restrictor should be connected to a length of deactivated fused silica capillary, inserted through the transfer line, and positioned flush with the aluminum MIP torch inset (Fig. 10.21). 

Figure 21 Supercritical fluid chromatography microwave induced plasma mass spectrometry (SFC-MIP-MS) torch interface. (From Ref. 113.)...

Okamoto Y. (1994) High-sensitivity microwave-induced plasma mass spectrometry for trace element analysis, J Anal At Spectrom 9 745-749. 

Shinohara a, Chiba M and Inaba Y (1999) Determination of germanium in human specimens comparative study of atomic absorption spectrometry and microwave-induced plasma mass spectrometry. 

Furuta, N., Ohata, M., Ichinose, T., Shinohara, A. and Chiba, M., Isotope-dilution analysis of selenium in human blood serum by using high power nitrogen microwave-induced plasma mass spectrometry coupled with a hydride-generation technique. Anal. Chem., 70, 2726-2730 (1998). 

Fecher P.A. A. Nagengast. (1994). Trace analysis in high matrix aqueous-solutions using helium microwave-induced plasma-mass spectrometry. /. Anal. At. Spectrom., Vol.9, ppl021-1027, ISSN 1364-5544... 

Creed J. X, Davidson T. M., Shen W. and Caruso (. A. (1990) Low-pressure helium microwave-induced plasma mass spectrometry for the detection of halogenated gas chromatographic effluents, J Anal At Spectrom 5 109-113. 

Shirasaki T. and Koizumi H. (2000) A multimicrospray nebulizer for microwave-induced plasma mass spectrometry, Anal. Chem. 72 2463-2467. 

Shinohara a., Chiba M. and Inaba Y. (1998) Determination of selenium concentrations in human blood plasma by microwave-induced plasma mass spectrometry, Anal. Set. 14 713-717. 

This chapter reviews and expands on the material presented by the authors at the 1987 Eastern Analytical Symposium. A short review of the work done in this area by other researchers will be presented for completeness. The primary focus will be on chromatographic sample introduction for plasma source MS. The use of ICP-MS for the detection of high performance liquid chromatography (HPLC) eluates will be discussed. Speciation of several As and Sn compounds found in the environment demonstrates the ability of ICP-MS to provide element specific detection at ultra-trace levels. In addition, gas chromatographic detection using He microwave-induced plasma mass spectrometry (MIP-MS) is shown to be a promising technique, particularly for the determination of halogenated species. 

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