Microarray immunological

The basal immunological mechanisms are complex but can now be analyzed with refined and more powerful laboratory methods, such as the microarray technique. With the help of this technique, additional information besides that concerning IgE and cytokine levels about the association between adaptive and innate immune response as well as other cellular responses can be gathered (6-8). 

Schoeters, E., Verheyen, G.R., Nelissen, I., Van Rompay A.R., Flooyberghs, J., Van Den Heuvel, R.L., Witters, H Schoeters, G.E., Van Tendeloo, V.F. and Berneman, Z.N. (2007) Microarray analyses in dendritic cells reveal potential biomarkers for chemical-induced skin sensitization. Molecular Immunology, 44, 3222-3233. 

Microarray analysis indicates that acute PVM infection is likewise accompanied by increased expression of mRNAs encoding interferon-beta and interferon response genes, as well as transcripts encoding proinflammatory chemokines CCL2, CCL5, CCL7 and CCLl 1. The contribution of these mediators to the cellular inflammatory response awaits formal immunologic and functional assessment. 

Microarrays, Second Edition Volume 1, Synthesis Methods, edited by Jang B. Rampal, 2007 Immunological Tolerance Methods and Protocols, edited by Paul J. Fairchild, 2007... 

Nomura, I. et al. (2003) Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis a gene microarray analysis. The Journal of Allergy and Clinical Immunology, 112, 1195-1202. 

V. Espina, E.C. Woodhouse, J. Wulfkuhle, H.D. Asmussen, E.F. Petricoin, L.A. Liotta, Protein microarray detection strategies focus on direct detection technologies. Journal of Immunological Methods 290 (2004) 121-133. 

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