Methyl p-Cresol

Fora (4-Methyl anisole, p-Cresyl methyl ether, p-Methoxy toluene or Methyl-p-Cresol), colorl... 

Bis [[2-(3,5-dimethyl-l-pyrazolyl)ethyl][2-(2-pyridyl)ethyl]amino]methyl -p-cresol... 

FEMA No. 2681 p-Cresyl Methyl Ether Methyl p-Cresol... 

Procedure Transfer 5 mL of sample into a 15-mm test tube, and add 10 mL of the Ferric Chloride Solution. The color of the solution is not a darker green than is a solution of 5 mL of a 1% solution of cresol in cresol-free methyl p-cresol mixed with 10 mL of the Ferric Chloride Solution. 

AI3-07621 Anisole, p-methyl- Benzene, 1-methoxy-4-methyl- EINECS 203-253-7 FEMA Number 2681 HSDB 5363 Methyl 4-methylphenyl ether Methyl p-cresol Methyl p-cresyl ether Methyl p-methylphenyl ether Methyl p-tolyl ether Methyl-para-cresol NSC 6254 Toluene, 4-methoxy-. Oil mp = -32° bp = 175.5° = 0,969 ... 

Synonyms p-Cresol methyl ether p-Cresyl methyl ether Methoxy-1 methyl-4 benzene 1-Methoxy-4-methylbenzene 4-Methoxytoluene p-Methoxytoluene 4-Methylanisole Methyl p-cresol 4-Methyl-1-methoxybenzene 4-Methylphenol methyl ether Methyl-p-tolyl ether p-Tolyl methyl ether Classification Aromatic ether Empirical CsHioO... 

Methyl-m-cresol. See 2,5-Xylenol Methyl p-cresol. See p-Methylanisole Methyl crotonate... 

Usually prepared from the corresponding sulphonic acids by alkali fusion, methylation of phenol or from the aminotoluene by treatment with nitrous acid followed by boiling. Both o- and p-cresol are used as end components in azo dyes. 

C7H80 P-CRESOL -127.446 3.1458E-01 2.B223E-05 -30.88 346 C8H18 3-METHYL- -216.803 7.5284E-01 6.2428E-05 13.72... 

The same author has shown by repetition of the early experiments already referred to (p. 507) that when yohimbine hydrochloride is distilled with zinc dust there is formed in addition to harman (XVII), p-cresol, which must originate from ring E of the yohimbine formula (XIV) by inclusion of C as the methyl group. Witkop s formula for yobyrine (IV6) received prompt confirmation by Clemo and Swan s synthesis of this base by... 

Mononitro Methyl Anisole (2-Nitro-4-methyl anisole, 3-Nitro4-methoxy l-methyl benzol or Methyl- [2-nitro4 methyl phenyl]-ether). CH3.0.(N02)C6H3.CH3, mw 167.18, N 8.38%, OB to C02-167.48%, pale yellow cryst, mp 8.5°, bp 274° (partial decompn), d 1.2025 g/cc at 25/4°, Rl 1.5536 si sol in eth (Ref 1). Prepd by heating K2-nitro-p-cresol with methyl-iodide methylalc in a sealed tube at 100°... 

As to the main limitation of MS vs. FTIR detection, namely the inability to distinguish closely related isomers, this rarely plays a role in additive analysis. Notable examples of isomeric additives are the bifunctional stabilisers C22H30O2S as 4,4 -thio-bis-(6-t-butyl-m-cresol), 2,2 -thio-bis-(4-methyl-6-f-butylphenol) and 4,4 -thio-bis-(2-methyl-6-f-butylphenol) (Section 6.3.6), the bisphenolic antioxidants C23H32O2 (Plastanox 2246 and Ethanox 720) and the phenolic antioxidants C15H24O (nonylphenol and di-f-butyl-p-cresol). 

A substitution of the methyl group in the para-position (Fig. 36) causes a larger expansion of the unit cell along c. The crystal packing of the resulting structure is still an efficient one, however the p-substituted methyl introduces already some steric hindrance into the structure the shortest distance of the methyl from its surroundings (adjacent phenyl walls ) is 3.56 A as compared to the normal van der Waals methyl — — phenyl distance of about 3.7 A49>. This steric misfit could be responsible for the preferential complexation of host 25 with m-cresol rather than with p-cresol. 

Figure 1 Effect of temperature on catalytic performance of Mg/Al/O catalyst in m-cresol methylation m-cresol conversion (u), selectivity to 3-MA (v), 2,3-DMP (X), 2,5-DMP (ct), 3,4-DMP (p), polyalkylates ( ).

Wang resin was purchased from Advanced ChemTech (1% DVB, 0.70mmol/g substitution, 100-200 mash, Cat. SA5009). Anhydrous tetrahydrofuran (THF), A/A-dimcthyl-formamide (DMF), methanol, dichloromethane, pyridine, 1,1 -carbonyldiimidazole (CDI), piperazine, homopiperazine, trans-1,4-diaminocyclohexane, 4-(dimethylamino)pyridine (DMAP), succinic anhydride, diglycolic anhydride, 3-methyl-glutaric anhydride, 2-aminophenol, 2-amino-p-cresol, 2-amino-4-tert-butyl phenol, /V-methylmorpholine (NMM), triphenylphosphine, diethyl azodicarboxylate (DEAD), and trifluoroacetic acid (TFA) were purchased from Aldrich Chemical Company, Inc. and used without further purification. PyBOP was purchased from Novabiochem. 

Synonyms AI3-00150 BRN 1305151 CCRIS 647 4-Cresol p-Cresol p-Cresylic acid EINECS 203-398-6 FEMA No. 2337 l-Hydroxy-4-methylbenzene p-Hydroxytoluene 4-Hydroxytoluene p-Kresol l-Methyl-4-hydroxybenzene 4-Methylhydroxybenzene p-Methyl-hydroxybenzene p-Methylphenol NSC 3696 4-Oxytoluene p-Oxytoluene Paracresol Paramethylphenol RCRA waste number U052 4-Toluol p-Toluol p-Tolyl alcohol UN 2076. 

CP 1309, see Pentachlorophenol CPD-244, see 2-Nittopropane CPD-926, see Dibenzofuran 4-CPPE, see 4-Chlorophenyl phenyl ether p-CPPE, see 4-Chlorophenyl phenyl ether Crag sevin, see Carbaryl Crawhaspol, see Trichloroethylene 2-Cresol, see 2-Methylphenol 4-Cresol, see 4-Methylphenol oCresol, see 2-Methylphenol p-Cresol, see 4-Methylphenol Crestoxo, see Toxaphene Crestoxo 90, see Toxaphene oCresylic acid, see 2-Methylphenol p-Cresylic acid, see 4-Methylphenol oCresyl phosphate, see Tri-ocresyl phosphate Crisalin, see Trifluralin Crisalina, see Trifluralin Crisfuran, see Carbofuran Crisulfan, see a-Endosulfan, p-Endosulfan Crisuron, see Diuron Crolean, see Acrolein Crop rider, see 2,4-D Crotenaldehyde, see Crotonaldehyde Crotilin, see 2,4-D Crotonal, see Crotonaldehyde Crotonic aldehyde, see Crotonaldehyde CRS, see Phenol Crunch, see Carbaryl Cryptogil OL, see Pentachlorophenol CS, see oChlorobenzylidenemalononitrile, Methyl mercaptan... 

In contrast to p-cresol, o-cresol does not undergo oxidation under these conditions. The same restriction is true in the case of 4-hydroxy-3,4 -dimethylbiphenyl—only one methyl group undergoes oxidation, the one in position 4 (KosheF et al. 1997). The methyl group that is in position 3—ortho with respect to the hydroxy group—remains intact. Such inactivity is explained in terms of the cation-radical mechanism according to Scheme 7.50. 

Structural information on aromatic donor molecule binding was obtained initially by using H NMR relaxation measurements to give distances from the heme iron atom to protons of the bound molecule. For example, indole-3-propionic acid, a structural homologue of the plant hormone indole-3-acetic acid, was found to bind approximately 9-10 A from the heme iron atom and at a particular angle to the heme plane (234). The disadvantage of this method is that the orientation with respect to the polypeptide chain cannot be defined. Other donor molecules examined include 4-methylphenol (p-cresol) (235), 3-hydroxyphenol (resorcinol), 2-methoxy-4-methylphenol and benzhydroxamic acid (236), methyl 2-pyridyl sulfide and methylp-tolyl sulfide (237), and L-tyrosine and D-tyrosine (238). Distance constraints of between 8.4 and 12.0 A have been reported (235-238). Aromatic donor proton to heme iron distances of 6 A reported earlier for aminotriazole and 3-hydroxyphenol (resorcinol) are too short because of an inappropriate estimate of the molecular correlation time (239), a parameter required for the calculations. Distance information for a series of aromatic phenols and amines bound to Mn(III)-substituted HRP C has been published (240). 

Synonyms Cresylic acid tricresol methyl-phenol o-cresol m-crtsoV, p-cresol hydroxytoluene... 

An important antioxidant for many products is butylated hydroxytoluene (BHT), more properly named 4-methyl-2,6-di-t-butylphenol. Acid-catalyzed electrophilic aromatic substitution of a t-butyl cation at the activated positions ortho to the hydroxy group of /)-cresol yields this product, p-Cresol is obtained from coal tar or petroleum. 

The oldest cresol production method used in the United States is through the recovery of fractional distillates from coal tars. Most domestic cresols are formed via catalytic and thermal cracking of naphtha fractions during petroleum distillation. Since 1965, quantities of coal tar and petroleum isolates have been insufficient to meet the rising demand. Consequently, several processes for the manufacture of the various isomers have been developed. One General Electric facility produces o-cresol at an annual capacity of 10,000 tons by the methylation of phenol in the presence of catalysts. The Sherman-Williams Company uses the toluene sulfonation process and maintains an annual capacity for p-cresol of 15,000 tons. The Hercules Powder Company produced p-cresol until 1972 by the cymene- cresol process. 

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