Meth A fibrosarcoma

They also express thanks to Prof. S. Suzuki, Prof. M. Suzuki, Prof. T. Matsumoto of Tohoku College of Pharmacy for the measurement of growth-inhibitory effects against MH134Y hepatoma and Meth-A fibrosarcoma in mice sc/iv. 

The importance of lymphocytes in cancer treatments based on LPS had been evoked by Parr et al. [61], Their role was later emphasized in A/J mice bearing SA-1 sarcoma or BALB/c mice bearing Meth A fibrosarcoma, treated with LPS [95], and in BDEX rats bearing PROb colon carcinoma, treated with bacterial extracts [96], Furthermore, SCID mice treated with intraperitoneal (i.p.) injections of LPS are unable to reject Meth A fibrosarcoma [96], However, lipid A treatment was efficient in nude mice bearing human pancreatic tumors [134]. 

Parr et al. [61] showed that lipid A has the same antitumoral effect as whole endotoxin preparations on murine L5178Y lymphoma. The effects of LPS and synthetic lipid A treatments were compared by Shimizu et al. [158-161] on Meth A fibrosarcoma in BALB/c mouse. The antitumoral activity of different lipids A has also been investigated. Ribi et al. [162] used an extract from S. typhimurium containing lipid A, which when injected directly into hepatocarcinoma line 10 tumors in guinea pigs shows an antitumoral effect. This activity is attributed to a monophosphoryl diglucosamine derivative of lipid A [163], Synthetic lipid A analogs also proved to be active in this system [164], as well as... 

Cells COS-7 cells (the African green monkey kidney fibroblast cell line), S-180 cells (mouse sarcoma), Meth-A fibrosarcoma cells (mouse fibrosarcoma), Jurkat cells (human T cell line). Colon 26 cells (mouse colon adenocarcinoma), B16BL6 cells (mouse meranoma). Human umbilical vein endothelial cells (HUVEC) (Kurabo Industries, Osaka, Japan). 

COS-7 cells and S-180 cells were cultured in DMEM supplemented with 10% heat-inactivated FBS. Meth-A fibrosarcoma cells and Jurkat cells were cultured with RPMI-1640 supplemented svith 10% heat inactivated FBS. Colon 26 cells... 

The growth of transplantable Meth A tumor was significantly suppressed in an Ag-specific manner when CVE was administered by not only an i.p. route [30], but orally as well [31]. It has been demonstrated that glycoprotein-rich substance (CVS) from the culture supernatant of Chlorella vulgaris strain CK displayed antitumor effect against experimental metastasis induced by Meth A fibrosarcoma [32]. 

Results of Tumor Implantation on the Flanks of Balb-C Mice after Co-Injection of Meth A Fibrosarcoma Cells And PG-MP as a Fimction of Surface Manipulation. 

Materials. Meth-A fibrosarcoma cells (RCB 0464) were purchased from Riken cell bank (Ibaraki, Tokyo, Japan), and macrophage-like J744-1 cells were generously supplied by the Cell Resource Center for Biomedical Research, Tohoku University (Miyagi, Japan) (4). RPMI 1640 medium was purchased from Gibco (Grand Island, New York), and fetal bovine serum (FBS) was from ICN Biomedicals (Costa Mesa, CA). WST-1 [2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt] and... 

Mice and Tumor Type. Female BALB/c mice, weighing 20 g were used. The Meth-A fibrosarcoma used was maintained in our laboratory in an ascitic form. Tumor cells (2.7 x 10 cells/animal) suspended in Hanks balanced salt solution (Gibco) were implanted intraperitoneally into mice. 

Fig. 4. Antitumor effect of liposomes on Meth-A fibrosarcoma-bearing BALB/c mice. Data are means SD, n = 6. P< 0.01 vs. Control. See Figure 1 legend for abbreviations.

Fig. 6. Effect of oxidized liposome on viability of Meth-A fibrosarcoma cells and macrophage-like J744-1 cells. Data are means SD, n = 6. P< 0.01, P< 0.05 vs. 0 p,g/mL. 2-DHA-PC/PS liposomes, 2-thiobarbituric acid value (TBA-V) = 1.62 0.12 nmol/mL. Soy PC/PS liposomes, TBA-V = 1.02 + 0.01 nmol/mL. See Figure 1 legend for abbreviations.

Metabolite/father compound ratios, 1099 Metabolomic, 2453 Metabolon, 1661 Metagenomic, 2445 Metal cofactors, 4044 Metallacyclopropane mechanism, 2704 Metallic ions, 1808 Metamphetamine abuse, 338 Metastasis, 3525, 3527, 3562 Metatranscriptomic, 2452 Meteloidine, 350 Methadone, 1082 Meth A fibrosarcoma, 988 Methamphetamine abuse, 334 Methamphetamines, 334, 912 Methanethiol, 2887, 2892, 2897, 2899 Methicillin-resistant Staphylococcus aureus (MRSA), 3429-3430 Methiin, 3666, 3667... 

Pectic polysaccharide, AR-4E-2, isolated from the roots of A, acutiloba showed a potent anti-tumor activity against the ascitic form of sarcoma-180, IMC carcinoma, and Meth A fibrosarcoma as well as the solid form of MM-46 tumor [90]. AR-4E-2 contained a rhamnogalacturonan core, and highly branched 3,5-arabinan and... 

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