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Metallodrugs

Ecker, D.J., Hempel, J.C., Sutton, B.M., Kirsch, R. and Crooke, S.T. (1986) Reactions of the metallodrug auranofin [(1-thio-p-D-glucopyranose-2,3,4,6-tetraacetato- S) (triethylphosphine) gold] with biological ligands studied... [Pg.315]

Various other strategies for investigating biodistributions of metallodrugs are being developed by different groups. [Pg.44]

Casini A, Gabbiani C, Michelucci E, Pieraccini G, Moneti G, Dyson PJ, Messori L (2009) Exploring metallodrug-protein interactions by mass spectrometry comparisons between platinum coordination complexes and an organometallic ruthenium compound. J Biol Inorg Chem 14 761-770... [Pg.76]

Timerbaev AR, Hartinger CG, Aleksenko SS, Keppler BK (2006) Interactions of antitumor metallodrugs with serum proteins advances in characterization using modem analytical methodology. Chem Rev 106 2224-2248... [Pg.79]

Polec-Pawlak K, Abramski JK, Semenova O, Hartinger CG, Timerbaev AR, Keppler BK, Jarosz M (2006) Platinum group metallodrug-protein binding studies by capillary electrophoresis - inductively coupled plasma-mass spectrometry a further insight into the reactivity... [Pg.79]

Figure 17.5 Skeleton structures of (a) polypyrrolic photosensitizers (i) porphyrin, (ii) chlorine, (Hi) bacteriochlorin, (iv) phthalocyanine, (v) naphthalocyanine, (vi) texaphyrin (b) examples of metalloderivatives (c) photosensitizers incorporating the metallodrug moieties (x-xii) cisplatin- and/or carboplatin-like structures, (xiii) iron sulphur nilrosy cluster... Figure 17.5 Skeleton structures of (a) polypyrrolic photosensitizers (i) porphyrin, (ii) chlorine, (Hi) bacteriochlorin, (iv) phthalocyanine, (v) naphthalocyanine, (vi) texaphyrin (b) examples of metalloderivatives (c) photosensitizers incorporating the metallodrug moieties (x-xii) cisplatin- and/or carboplatin-like structures, (xiii) iron sulphur nilrosy cluster...
Groessl, M., Terenghi, M., Casini, A., Elviri, L., Lobinski, R., Dyson, P.J. Reactivity of anticancer metallodrugs with serum proteins new insights from size exclusion chromatography-ICP-MS and ESI-MS. J. Anal. At. Spectrom. 25, 305-313 (2010)... [Pg.395]

Groessl, M., Hartinger, C.G. Anticancer metallodrug research analytically painting the omics picture-current developments and future trends. Anal. Bioanal. Chem. 405, 1791-1808 (2013)... [Pg.397]

GroessI, M., Tsybin, Y.O., Hartinger, C.G., Keppler, B.K., Dyson, P.J. Ruthenium versus platinum interactions of anticancer metallodrugs with duplex oligonucleotides characterized by electrospray ionization mass spectrometry. J. Biol. Inorg. Chem. 15, 677-688 (2010)... [Pg.400]

Szpunar, J., Makarov, A., Lobinski, R., Pieper, T., Keppler, B. K. Investigation of metallodrug-protein interactions by size-exclusion chromatography coupled with inductively coupled plasma mass spectrometry (ICP-MS). Anal Chim Acta 1999, 387, 135-144. [Pg.268]

These studies (Figure 9), using NMR studies of 31P and other nuclei, have developed a detailed picture of the reactions of auranofin and its metabolites in blood. They demonstrate the applicability of NMR to elucidating metallodrug pharmacology and reactivity. [Pg.96]

Hadjiliadis, N. and Sletten, E. (eds) (2009) Metal Complex — DNA Interactions, Wiley-Blackwell, Oxford, UK. Overviews metal-DNA interactions and mechanisms, metallodrugs and toxicity includes a deep coverage of cisplatin. [Pg.267]

See other pages where Metallodrugs is mentioned: [Pg.80]    [Pg.22]    [Pg.44]    [Pg.58]    [Pg.646]    [Pg.351]    [Pg.60]    [Pg.73]    [Pg.76]    [Pg.313]    [Pg.354]    [Pg.432]    [Pg.5446]    [Pg.5465]    [Pg.5466]    [Pg.5466]    [Pg.5467]    [Pg.5469]    [Pg.5470]    [Pg.399]    [Pg.19]    [Pg.251]    [Pg.251]    [Pg.252]    [Pg.252]    [Pg.255]    [Pg.265]    [Pg.563]    [Pg.578]    [Pg.579]   
See also in sourсe #XX -- [ Pg.96 ]

See also in sourсe #XX -- [ Pg.493 , Pg.494 , Pg.495 , Pg.498 , Pg.564 , Pg.565 , Pg.581 , Pg.584 , Pg.585 ]



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Cellular Localization of Metallodrugs

Metallodrug-Biomolecule Interactions

Metallodrug-protein interactions

Metallodrugs biomolecule interactions

Metallodrugs interactions

Metallodrugs metallodrug-protein interactions

Other Metallodrugs

Pharmacokinetics of Metallodrugs

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