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Metabolism of lignans

Metabolism of Lignans and their Phyto-Estrogenic Activity.613... [Pg.585]

METABOLISM OF LIGNANS AND THEIR PHYTO-ESTROGENIC ACTIVITY... [Pg.613]

SP Borriello, KDR Setchell, M Axelson, AM Lawson. Production and metabolism of lignans by human faecal flora. JAppl Bacterial 58 37-43, 1985. [Pg.628]

ROWLAND I R, WISEMAN H, SANDERS T A, ADLERCREUTZ H and BOWEY E A (2000) luteriudividual variation in metabolism of soy isoflavones and lignans influence of habitual diet on equol production by the gut microflora. Nutr Cancer 36, 27-32. [Pg.105]

Recently, some of the specific faecal bacteria involved in the metabolism of dietary isoflavonoids were isolated (Hur et al., 2000). They have been shown to selectively convert genistin and daidzin to their respective aglycones. One of the isolated bacteria, under anoxic conditions, was further shown to metabolise genistein and daidzein to their respective dihydroxy-genistein and dihydroxy-daidzein. In the case of lignans, enterodiol and enterolactone were shown to be excreted in vivo only in rats harbouring a gut microflora (Rowland et al, 1999). [Pg.195]

MORTON M S, MATOS-FERREIRA A, ABRANCHES-MONTEIRO L, CORREIA R, BLACKLOCK N, CHAN P S, CHENG 0, LLOYD s, CHIEH-PING w and GRIFFITHS K (1997) Measurement and metabolism of isoflavonoids and lignans in the human male. Cancer Lett. 114 (1-2) 145-51. [Pg.217]

Substantial individual differences were observed in the response to study breads and the ranges of enterolactone concentration changes in the groups were as follows -54.5-60.0 nmol/1 (placebo), -26.2-101.3 nmol/1 (LP), -19.6-81.8 nmol/1 (HP). This was something that could have been expected as in several studies dietary factors have explained only 10% of the variation in serum enterolactone (Vanharanta et al, 2002b Kilkkinen et al., 2001). This gives further support to the major role of intestinal bacteria in the synthesis of enterolactone. Decreased concentrations of enterolactone may occur due to an increased fiber intake, which may shorten the retention time in the colon and lead to incomplete metabolism of plant lignans. Constipation was earlier shown to be associated with an increased level of serum enterolactone (Kilkkinen et al., 2001). [Pg.291]

Heinonen, S., Nurmi, T., Liukkonen, K., Poutanen, K., Wahala, K., Deyama, T., Nishibe, S., and Adlercreutz, H., In vitro metabolism of plant lignans new precursors of mammalian lignans enterolactone and enterodiol, J. Agric. Food Chem., 49, 3178, 2001. [Pg.358]

Bowey E, Aldercreutz A, Rowland I. Metabolism of isoflavones and lignans by the gut microflora a study in germ-free and human flora associated rats. Food Chem. Toxicol. 41, 631-636, 2003. [Pg.389]

Jacobs, E. and Metzler, M. 1999. Oxidative metabolism of the mammalian lignans enterolactone and enterodiol by rat, pig, and human liver microsomes. J. Agric. Food Chem. 47, 1071— 1077. [Pg.84]

As mentioned earlier that sesame lignans, especially sesamin and epi-sesamin, could influence the metabolism of polyunsaturated fatty acid and the production of prostaglandins. As prostaglandin is one of the most influential factors for mammary carcinogenesis, Hirose et al. (99) studied the effect of sesamin on dimethylbenz-anthracene (DMBA)-induced mammary cancer. Their results showed that sesamin at a dietary level of 0.2% considerably reduced the cumulative number and mean number of mammary cancer the effectiveness of sesamin was similar to a-tocopherol. [Pg.1204]

S Heinonen, T Nurmi, K Liukkonen, K Potanen, K Wahala, T Deyama, S Nishibe, Adlercreutz. In Vitro Metabolism of plant bgnans New precursors of mammalian lignans enterolactone and enterodiol. J Agric Food Chem 49 3178-3186, 2001. [Pg.627]

Expression of Lignans in Rice Crain via Metabolic Engineering... [Pg.943]


See other pages where Metabolism of lignans is mentioned: [Pg.358]    [Pg.77]    [Pg.585]    [Pg.613]    [Pg.628]    [Pg.173]    [Pg.282]    [Pg.232]    [Pg.358]    [Pg.77]    [Pg.585]    [Pg.613]    [Pg.628]    [Pg.173]    [Pg.282]    [Pg.232]    [Pg.195]    [Pg.294]    [Pg.496]    [Pg.358]    [Pg.358]    [Pg.245]    [Pg.341]    [Pg.46]    [Pg.46]    [Pg.89]    [Pg.134]    [Pg.317]    [Pg.945]    [Pg.543]    [Pg.206]    [Pg.246]    [Pg.257]    [Pg.261]   
See also in sourсe #XX -- [ Pg.195 ]




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