Metabolism general aspects

It has been decided as a general scheme that the volumes first issued shall deal with the pure chemistry of physiological products and with certain general aspects of the subject. Subsequent monographs will be devoted to such questions as the chemistry of special tissues and particular aspects of metabolism. So the series, if continued, will proceed from physiological chemistry to what may be now more properly termed chemical physiology. This will depend upon the success which the first series achieves, and upon the divisions of the subject which may be of interest at the time. 

It is necessary to pay attention to the fact that, during recent years, the bioinorganic properties of aluminum coordination compounds have become the objects of detailed study their general aspect [354], metabolism and toxicology [355,356], complex formation with nucleozides of di- and triphosphates and nucleo-zide-bound proteins [357], and x-ray analysis of biologically important complexes... 

W2. Wadman, S. K., Inborn errors of amino acid metabolism chemical aspects of diagnosis and control of treatment. Suggestions for a general analytical approach. In Brain Damage by Inborn Errors of Metabolism, Symp. Interdisciplinary Soc. Biol. Psychiat., pp. 48-59. Bohn, Haarlem, 1968. 

The more general the point of view is (the higher the level), the less applicable becomes a rule to describe a detail. On the other hand, a more specific description lets us derive the underlying general aspects. An example is the definition of life. In a specific rule we can define life from our experience with life forms on our planet consumption, metabolization, and growth are some commonly used criteria for life from a discrete point of view. If we define a rule on the basis of these criteria in a computer program, it would look like this ... 

General Aspects of Iodine Sources and Intakes in the Diet, Main Routes of Iodine Metabolism, and Metabolic Roles... 

Accurate data acquisition is essential for successful metabolic studies. The current trend from HPLC-based to LC/MS/MS-based analytical tools in ADME research, particularly in the pharmaceutical industry, demonstrates this requirement for accurate data acquisition. General aspects of the operation of LC/MS/MS are described below, together with a brief overview of traditional HPLC systems. 

Both metabolism sensors and affinity sensors can be designed using electrochemical transducers for the signal generation, as will be discussed in detail below. However, before evaluating specific features of electrochemical biosensors, some general aspects of the qualification of biosensor properties have to be discussed. 

References for Further Reading General Aspects of Secondary Metabolism... 

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