Amides mercury

Neutral Homoleptic Zinc, Cadmium and Mercury Amides... 

Mercury peroxide, 4601 Mercury(I) azide, 4607 Mercury(I) bromate, 0270 Mercury(I) chlorite, 4074 Mercury cyanamide, 0520 Mercury fluoride, 4306 Mercury hypophosphate, 4612 Mercury nitrate, 4604 Mercury oxide , 4608 Mercury thionitrosylate, 4605 Mercury ) 5-nitrotetrazolide, 0977 Mercury ) acetylide, 0971 Mercury ) ao-dinitromethanide, 0703 Mercury ) amide chloride, 3993 Mercury ) azide, 4599 Mercury ) bromate, 0269 Mercury ) bromide, 0268 Mercury ) chlorite, 4071... 

MERCURY AMIDE CHLORIDE (10124-48-8) Reacts violently with halogens barium, chlorine, fluorine, and metal salts of amines. Contact with acids or acid fumes causes decomposition, producing hydrogen chloride fumes. Incompatible with organic anhydrides, acrylates, alcohols, aldehydes, alkylene oxides, substituted allyls, cresols, caprolactam solution, epichlorohydrin, ethylene dichloride, glycols, isocyanates, ketones, maleic anhydride, nitrates, nitromethane, phenols, vinyl acetate. May corrode aluminum, copper, zinc, and some stainless steel in the presence of moisture. 

Mercuric Chloride, Ammoniated. Mercury amide chloride arninomercuric chloride mercury ammonium chloride ammoniated mercury white precipitate white mercuric... 

Aminomercuric chloride Aminomercury chloride Ammoniated mercuric chloride Ammoniated mercury EINECS 233-335-8 HSDB 1175 Hydrargyrum ammonialum Hydrargyrum praecipitatum album Hydrargyrum precipitatum album Lemer/s white precipitate Mercuric amidochloride Mercuric ammonium chloride Mercuric chloride, ammoniated Mercury amide chloride (Hg(NH2)CI) Mercury amide chloride Mercury amine chloride Mercury, ammoniated Mercury ammonium chloride Mercury, ammonobasic (HgNHjCI) Mercury(ll) chloride ammonobasic Quecksilber(ll)-amid-chlorid UN1630 White mercuric precipitate White mercury precipitated White precipitate. Mercury ammonium chloride, used for the preparation of cinnabar and in medicine as a topical anti-intective. Powder d = 5.38 insoluble in H2O, EtOH, soluble in mineral xids. 

Mercury, aceto(chloromethoxypropyl)- Mercury, acetoxy (chloromethoxypropyl)-. See Chloromethoxy propyl mercuric acetate Mercury, acetoxy (2-methoxyethyl)-. See Methoxyethylmercury acetate Mercury-amide-chloride Mercury (II) amidochloride Mercury amine chloride Mercury ammoniated. See Mercury ammonium chloride... 

Synonyms aminomercuric chloride mercuric ammonium chloride mercury ammonium chloride mercury amide chloride Uses inorganic mercurial compound used in creams as a topical anti-infective agent (formerly used in the treatment of psoriasis and in skin-lightening formulations)... 

Divalent metal silylamide complexes are easily obtained from the interaction of the corresponding REM with mercury amide in DME medium at room temperature [15] ... 

Acid amides have weakly amphoteric properties, and thus give salts such as CjHsCONHj.HCl with strong acids, and salts of the type C HsCONHNa with strong bases. These compounds have to be prepared at low temperatures to avoid hydrolysis, and are difficult to isolate. The mercury derivatives can, however, usually be readily prepared, because mercuric oxide is too feebly basic to cause hydrolysis of the amide, and the heavy mercuric derivatives crystallise well. 

Alkynyl anions are more stable = 22) than the more saturated alkyl or alkenyl anions (p/Tj = 40-45). They may be obtained directly from terminal acetylenes by treatment with strong base, e.g. sodium amide (pA, of NH 35). Frequently magnesium acetylides are made in proton-metal exchange reactions with more reactive Grignard reagents. Copper and mercury acetylides are formed directly from the corresponding metal acetates and acetylenes under neutral conditions (G.E. Coates, 1977 R.P. Houghton, 1979). 

The reaction of alkenyl mercurials with alkenes forms 7r-allylpalladium intermediates by the rearrangement of Pd via the elimination of H—Pd—Cl and its reverse readdition. Further transformations such as trapping with nucleophiles or elimination form conjugated dienes[379]. The 7r-allylpalladium intermediate 418 formed from 3-butenoic acid reacts intramolecularly with carboxylic acid to yield the 7-vinyl-7-laCtone 4I9[380], The /i,7-titisaturated amide 421 is obtained by the reaction of 4-vinyl-2-azetidinone (420) with an organomercur-ial. Similarly homoallylic alcohols are obtained from vinylic oxetanes[381]. 

Acetoiicetyliition Reactions. The best known and commercially most important reaction of diketene is the aceto acetylation of nucleophiles to give derivatives of acetoacetic acid (Fig. 2) (1,5,6). A wide variety of substances with acidic hydrogens can be acetoacetylated. This includes alcohols, amines, phenols, thiols, carboxyHc acids, amides, ureas, thioureas, urethanes, and sulfonamides. Where more than one functional group is present, ring closure often follows aceto acetylation, giving access to a variety of heterocycHc compounds. These reactions often require catalysts in the form of tertiary amines, acids, and mercury salts. Acetoacetate esters and acetoacetamides are the most important industrial intermediates prepared from diketene. 

The biochemical basis for the toxicity of mercury and mercury compounds results from its ability to form covalent bonds readily with sulfur. Prior to reaction with sulfur, however, the mercury must be metabolized to the divalent cation. When the sulfur is in the form of a sulfhydryl (— SH) group, divalent mercury replaces the hydrogen atom to form mercaptides, X—Hg— SR and Hg(SR)2, where X is an electronegative radical and R is protein (36). Sulfhydryl compounds are called mercaptans because of their ability to capture mercury. Even in low concentrations divalent mercury is capable of inactivating sulfhydryl enzymes and thus causes interference with cellular metaboHsm and function (31—34). Mercury also combines with other ligands of physiological importance such as phosphoryl, carboxyl, amide, and amine groups. It is unclear whether these latter interactions contribute to its toxicity (31,36). 

A MIXTURE of 120 g. (3 moles) of sodamide (Note i) and 200 cc. of purified mineral oil (Note 2) is ground together in a mortar until the amide is finely pulverized (Note 3). This suspension is transferred to a 2-I. round-bottom, three-necked flask fitted with a reflux condenser holding a calcium chloride tube, a 500-cc. separatory funnel, and an efficient mechanical stirrer through a mercury seal. The mortar and pestle are rinsed with an additional 250 cc. of the oil which is then added to the reaction flask. This is heated in an oil bath maintained at 160-165, the stirrer is started and 203 g. (i mole) of cyclohexylbromopropene (p. 20) is dropped in during one and one-half hours. Ammonia is evolved and this is allowed to pass through the condenser and is collected in water. 

Mercury Nitride. Hg3N2, mw 629,78, N 4.45%, brown powd, mp (explds). Sol in amm hydroxide, dil acids, coned nitric acid and amm salts. Prepd by adding a soln of mercuric iodide or bromide to an excess of a soln of K amide in liq ammonia (Refs 1-3)... 

The organo-corrinoids show similar behavior, but also additional complications. Rate constants have been determined 84) for the attack of mercury(II) acetate on various organocobalt cobinamides (X = H2O or absent) and cobalamins (X = 5,6-dimethylbenziminazole). The first complication, which has to be born in mind when comparing the cobinamides with the cobalamins or DMG complexes, is that the organocobin-amides are partly (R = vinyl and methyl) or wholly (R = Et, -Pr, t-Pr,... 

---