Melilotus officinalis

Dicoumarol Coumarin Anti-coagulant Melilotus officinalis... 

Melilotus officinalis Lamk. Flavonoids, resin, tannins, coumarins, hydroxycoumarin, hydrocoumarin.99107 Reduce the risk of phlebitis and thrombosis, sedative, antispasmodic. 

Eucalyptus citriodora, E. globulus Cuscuta chinensis, C. epithymum Melilotus officinalis Syringa suspensa, S. vulgaris... 

Sweet clover (Melilotus officinalis Desr) honey has a delicious flavor and is considered one of the best honeys. 

The simple coumarin nucleus (Fig 7.3), which is derived by lactone formation of an ortho-hydroxy-czs cinnamic acid, is a common metabolite in higher plants and is often found in glycosidic form. Coumarins are common in Api-aceae, in certain genera of Fabaceae (e.g. Dipteryx odorata, Melilotus officinalis), Poaceae (e.g. Anthoxanthum odoratum) and Rubiaceae (e.g. Galium odoratum). However, proliferation of coumarins to the status of major chemical markers occurs in only a few cases, most notably, but not exclusively, in the Api-aceae (subfamily Apioideae) and in the Rutaceae (Gray and Waterman, 1978 Murray et al., 1982). In these cases, the coumarin nucleus has almost invariably been embellished by the addition of a prenyl unit leading to furocoumarin (Fig 7.3) and pyranocoumarin structures. 

Sweet clover has a long history of medicinal use, often as an antiflammatory or analgesic preparation in the form of ointments and poultices. Melilotus officinalis (yellow sweet clover, or ribbed melilot) was reputed to have been a favorite herbal treatment used by King Henry VIII of England and the plant is still referred to as King s Clover in some publications (175). 

Warfarin Blood thinner for clots Melilotus officinalis Sweet clover... 

Melilotus officinalis (sweet clover) contains coumarin, 3,4-dihydrocoumarin (melilotine), ortho-coumaric acid, ortho-hydroxycoumaric acid, and the ortho-glucoside of ortho-coumaric acid (melilotoside). Withering of the plant leads to enzymatic glycoside hydrolysis and the resulting ortho-coumaric acid is spontaneously transformed to coumarin the dried herb therefore smells strongly of coumarin (see separate monograph). M. officinalis has been used to treat lymphedema and the edema of chronic venous insufficiency. 

Melilotus officinalis (sweet clover) Myroxylon species (balsam of Peru) Pithecollobium jiringa (jering fruit) Sophora falvescens (Ku shen) Trifolium pratense (red clover) Gentiana species (gentian)... 

Melaleuca alternilolia (tea tree) Melilotus officinalis (sweet clover) Mentha piperita (peppermint) Mentha pulegium (pennyroyal) Momordica charantia (karela fruit, bitter melon)... 

Melilotus Leaves and flower- Melilotus officinalis Europe... 

BOIA A Vitamin K antagonist This group comprises vitamin K antagonists such as the dicoumarol group. The plant Melilotus officinalis (L.) Pallas, family Fabaceae, that has become mouldy due to microorganisms, caused disease in grazing cows, Sweet Clover Disease , where the cows died ftom internal bleeding. The discovery that this disease was... 

Sensitive species are those, which are gradually eliminated from the polluted area, such as Capsella bursa-pastoris, Cardaria dvaba, Cichorium in-tybus, Dactylis glomerata, Stellaria media, Veronica hederifolia, Hypericum perforatum, Plantago major, Papaver rhoeas, Viola tricolor, Melilotus officinalis, Onopordum acanthium, Symphytum officinale. Ranunculus arven-... 

Medicago polymorpha 143 Melia azedarach 231 Melilotus officinalis 143 Menisperum dauricum 336 Mentha piperita 373,376 Metridium senile 347 Micrococcus luteus 343 Mollugo glinus 176 Momordica chranlia 189... 

A 66-year-old taking acenocoumarol, levothyroxine and prazepam had an increase in her INR after massaging a proprietary topical cream Cyclo 3) containing melilot Melilotus officinalis sweet clover) and butcher s broom Ruscus aculeatus) on her legs three times daily. On the first occasion her INR rose from about 2 to 5.8 after 7 days of use, and on a later occasion it rose to 4.6 after 10 days of use. ... 

Martino E, Ramaiola I, Urbano M, Bracco F, Collina S (2006) Microwave-assisted extraction of coumarin and related compounds from Melilotus officinalis (L.) Pallas as an alternative to Soxhlet emd ultrasound-assisted extraction. J Chromatogr A 1125(2) 147-151 Mashkovskii MD (1953) The pharmacology of tropacin. Farmeikol Toksikol (5) 3-8 (in Russian)... 

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