Dipteryx odorata

Tonka bean absolute is prepared by solvent extraction either directly from so-called Tonka beans or via the concrete. Tonka beans are the seeds of fruits from Dipteryx odorata (Aubl.) Willd. (Fabaceae). 

Coumarin was first isolated by Vogel in 1820 by extraction from tonka beans (Dipteryx odorata). It was subsequently identified in a large number of plants belonging to many different families. Its better known occurrences are in sweet clover (Melilotus alba and M. officinalis), sweet woodruff (Asperula odorata), vanilla leaf (Trilisa odoratissima), vanilla beans (Vanillaplanifolia), cassia (Cinnamorum cassia), lavender (Lavendula officinalis) and balsam of Peru (Myroxylon pereirae) (Perone, 1972 Maries et al, 1987 Boisde Meuly, 1993 Budavari, 1998). 

Benzopyran-2-one Dipteryx odorata (Fabaceae), Myroxylon mown grass]... 

The simple coumarin nucleus (Fig 7.3), which is derived by lactone formation of an ortho-hydroxy-czs cinnamic acid, is a common metabolite in higher plants and is often found in glycosidic form. Coumarins are common in Api-aceae, in certain genera of Fabaceae (e.g. Dipteryx odorata, Melilotus officinalis), Poaceae (e.g. Anthoxanthum odoratum) and Rubiaceae (e.g. Galium odoratum). However, proliferation of coumarins to the status of major chemical markers occurs in only a few cases, most notably, but not exclusively, in the Api-aceae (subfamily Apioideae) and in the Rutaceae (Gray and Waterman, 1978 Murray et al., 1982). In these cases, the coumarin nucleus has almost invariably been embellished by the addition of a prenyl unit leading to furocoumarin (Fig 7.3) and pyranocoumarin structures. 

The seeds of Dipteryx odorata (Dutch tonka bean) and Dipteryx oppositofolia (EngUsh tonka bean) are said to yield 1-3% of the non-anticoagulant coumarin, which is covered in a separate monograph. 

Tonka bean DIpteryx odorata 1 Coumarin glycosides (see p 378)... 

Dipteryx odorata (family Leguminosae Papilionoideae) Commonly... 

Isol. from Cladrastis platycarpa, C. shikokiana and Dipteryx odorata. Cryst. (CHCl3/Et20). Mp 235-237°. The name Dipteryxin has also been given to 7,8-Dihydroxy-4, 6-dimethoxyisoflavone from D. odorata therefore the name Isoplatycarpanetin is preferred here. 

Isol. from Cordyla africana and Dipteryx odorata. Cryst. (CHClj/EtjO). Mp 172-174°. The name Odoratin(e) has also been used for 3, 7-Dihydroxy-4, 6-dimethoxy-isoflavone from D. spp., and additionally for at least 3 other nat. prods. 

Isol. from Dipteryx odorata heartwood and Pterodon apparicioi trunkwood. There are at least three other odoratins. 

Isol. from heartwood of Dalbergia retusa and Dipteryx odorata. Cryst. (Me2CO/MeOH or Me2CO). Mp 249°. 4, 8-Di-Me ether [37816-20-9]. 7-Hydroxy-4 dimethoxyisoflavone. %-O-Methylretusin C17H14O5 M 298.295... 

Coumarin, which was first isolated from tonka bean Dipteryx odorata Wild) in 1820 [36], have been demonstrated to possess anti-inflammatory, antiplatelet aggregation, antidote, antitumor, and AChE inhibitory activities [37]. As a consequence, significant efforts have been devoted to the synthesis of coumarins. 

Coumarins are phenolic compounds widely distributed in the plant kingdom. The isolation of coumarin was first reported by Vogel in 1820 [1,2]. The name coumarin originates from a Caribbean word coumarou for the Tonka tree (Dipteryx odorata WUld, Leguminosae), which shares the characteristic smeU of these compounds and was known botanically at one time as Coumarouna odorata Aubl. 

Cumani - Tonka Bean Dipteryx odorata seed up to 3.0 coumaiin 11... 

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