Medicine glucose testing

Glucose Test. Faculty of Medicine, Charles University, Praha, Czech Republic (http //www.lf3. cuni.cz/ustavy/chemie/eng/first/ls/a4.doc). 

Lee, J.H., and Kost, G.J. (2000) Point-of-care glucose testing-effects of critical care variables, influence of reference instruments, and a modular glucose meter design. Archives of Pathology i Laboratory Medicine, 124 (2), 257-266. 

In clinical medicine, the tests most often used to detect abnormalities of carbohydrate metabolism are determination of glucose excretion in the urine and estimation of the glucose concentration in the blood during fasting and after administration of a large dose of glucose (glucose tolerance... 

Biosensors with their oft-quoted (ideal) properties would seem to be ready partners for industrial analysts who want information at point-of-need, but as has been pointed out many times, few examples have had the same success as the blood glucose sensors for use in the home (albeit this is an example from medicine rather than industry). The reasons for this have also been pointed out many times, the principal one being that the development and manufacture of the blood glucose sensors is supported by the sadly huge market for diabetic testing and the large amount of investment capital which accrues to that market [6,7]. Further, blood is a sample of reasonably constant composition (in this context), the information is truly useful to the client and the desire for information at home means there is less competition from laboratory-based instruments. This is in contrast to the diverse requirements for analysis in the food industry (for example) which make up a series of... 

The function of clinical chemistry in toxicology (as well as in human and veterinary medicine) is to provide, via laboratory analysis, evaluations of the qualitative and quantitative characteristics of specific endogenous chemical components present in samples of blood, urine, feces, spinal fluid, and tissues. The purpose is to help identify abnormal or pathological changes in organ system functions. The most common specimens used in clinical chemistry are blood and urine, and many different tests exist to test for almost any type of chemical component in blood or urine for example, blood glucose, electrolytes, enzymes, hormones, lipids (fats), other metabolic substances, and proteins. The tests used were all initially applied to human clinical medicine, and may not possess the same utility when performed as part of nonclinical toxicity studies in a wide variety of other species. 

Tang, Z.P., Louie, R.F., Lee, J.H., Lee, D.M., Miller, E.E., and Kost, G.J. (2001) Oxygen effects on glucose meter measurements with glucose dehydrogenase- and oxidase-based test strips for point-of-care testing. Critical Care Medicine, 29 (5), 1062-1070. 

Many natural drugs and traditional preparations are used in traditional medicine as antidiabetics and several active compounds have been identified by in vivo bioassay using experimental diabetic animal induced by alloxan or streptozocin or by using the oral sucrose tolerance test (one of the animal model of insulin-dependent diabetes mellitus) and by in vitro bioassay testing glucose transport activity. 

Medicine The oral glucose tolerance test is a diagnostic tool for early diabetes mellitus. The results... 

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