Materials biomaterials

Sundback CA, Shyu JY, Wang YD, Faquin WC, Danger RS, Vacanti JP, and Hadlock TA. Biocompatibility analysis of poly(glycerol sebacate) as a nerve guide material. Biomaterials, 2005, 26, 5454-5464. 

Nakayama Y., Miyamura M., Hirano Y., Goto K., Matsuda T., Preparation of poly(ethylene glycol)-polystyrene block copolymers using photochemistry of dithiocarbamate as a reduced cell-adhesive coating material, Biomaterials 1999 20 963-970. 

Badylak SF (2007) The extracellular matrix as a biologic scaffold material. Biomaterials 28 (25) 3587-3593... 

S. Radin and P. Ducheyne, Controlled release of vancomycin from thin sol-gel films on titanium alloy fracture plate material, Biomaterials, 2007, 28, 1721. 

X. Xu, J.O. Burgess, Compressive strength, fluoride release and recharge of fluoridereleasing materials. Biomaterials 24 (2003) 2451-2461. 

Introducing chirality into polymers has distinctive advantages over the use of nonchiral or atactic polymers because it adds a higher level of complexity, allowing for the formation of hierarchically organized materials. This may have benefits in high-end applications such as nanostructured materials, biomaterials, and electronic materials. Synthetically, chiral polymers are typically accessed by two methods. Firstly, optically active monomers - often obtained from natural sources - are polymerized to afford chiral polymers. Secondly, chiral catalysts are applied that induce a preferred helicity or tacticity into the polymer backbone or activate preferably one of the enantiomers [59-64]. 

Marques, A. R., Reis, R. L., Hunt, J. A. (2001). In vitro evaluation of the biocompatibility of novel starch based polymeric and composite material. Biomaterials., 21,1471-1478. 

Polyelectrolytes have been widely investigated as components of biocompatible materials. Biomaterials come into contact with blood when used as components in invasive instruments, implant devices, extracorporeal devices in contact with blood flow, implanted parts of hard structural elements, implanted parts of organs, implanted soft tissue substitutes and drug delivery devices. Approaches to the development of blood compatible materials include surface modification to give blood compatibility, polyelectrolyte-based systems which adsorb and/or release heparin as well as polyelectrolytes which mimic the biological activity of heparin. 

McKenzie JL, Waid MC, Shi R et al (2004) Decreased functions of astrocytes on carbon nanofibre materials. Biomaterials 25 1309-1317... 

Meyers SR, Khoo XJ, Huang X et al (2009) The development of peptide-based interfacial biomaterials for generating biological functionality on the surface of bioinert materials. Biomaterials 30(3) 277-286... 

Amitai G, Andersen J, Wargo S et al. (2009) Polyurethane-based leukocyte-inspired biocidal materials. Biomaterials 30 6522-6529... 

A second approach to better understand the development of new materials (biomaterials for instance) is the following. If a present material becomes scarce or too expensive, another material, more abundant and/or cheaper, can be used provided it fulfils the basic requirements of performance. For instance, accessory metal parts in cars were replaced by reinforced plastic because of the lower price and lower weight during the period of a steel crisis. 

Dal Pra, I., Freddi, G., Minic, J., Chiarini, A., and Armato, U. "De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials". Biomaterials 26(14), 1987-1999 (2005). 

Rowley JA, Madlambayan G, and Mooney DJ. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 1999 20 45-53. 

Ranucci CS, Kumar A, Batra SP, Moghe PV (2000) Control of hepatocyte function on collagen foams sizing matrix pores toward selective induction of 2-D and 3-D cellular morphogenesis. Biomaterials 21(8) 783-793 Rowley JA, Madlambayan G, Mooney DJ (1999) Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 20(1) 45-53... 

Santeire JP et al (2005) Understanding the biodegradation of polyurethanes From classical implants to tissue engineering materials. Biomaterials 26(35) 7457-7470 Demir MM et al (2002) Electrospinning of polyurethane fibers. Polymer 43(11) 3303-3309... 

Viitala, R. et al.. Surface properties of in vitro bioactive and non-bioactive sol-gel derived materials. Biomaterials. 23, 3073, 2002. 

Bokhari M.A., Akay G., Birch M.A., Zhang S. 2005. The enhancement of osteoblast growth and differentiation in vitro on a peptide hydrogel - PolyHIPE Polymer hybrid support material. Biomaterials, 26, 5198-5208 (in press). 

Chen G-Q, Wu Q (2005) The apphcation of polyhydroxyalkanoates as tissue engineering materials. Biomaterials 26 6565-6578... 

Li X-T, Zhang Y, Chen G-Q (2008) Nanofibrous polyhydroxyalkanoate matrices as cell growth supporting materials. Biomaterials 29 3720-3728 Lim S, Teong LK (2010) Recent trends, opportunities and challenges of biodiesel in Malaysia an overview. Renew Sustain Energy Rev 14 938-954 Lim YY, Sudesh K (Unpublished). 

A.M. Young, S.A. Raffeka, J. A. Hewlett, FTIR investigation of monomer polymerisation and polyacid neutralisation kinetics and mechanisms in various aesthetic dental restorative materials. Biomaterials 25 (2004) 823-833. 

A. Oloffs, C. Grosse-Siestrup, S. Bisson, M. Rinck, R. Rudolph, U. Gross, Biocompatibility of silver-coated polyurethane catheters and silver-coated Dacron material. Biomaterials 15 (10) (1994) 753-758. 

J. Kohn, R. Langer, Bioresorbable and bioerodible materials. Biomaterials Science An Introduction to Materials in Medicine, Academic Press, San Diego, 1996, pp. 64—72. 

Yaszemski, M. J., Payne, R. G., Hayes, W. C., Langer, R. Mikos, A. G. (1996) In vitro degradation of a poly(propylene fumarate)-based composite material. Biomaterials, 17, 2127-2130. 

Rowley, J. A., Madlambayan, G. Mooney, D. J. (1999) Alginate hydrogels as S3mthetic extracellular matrix materials. Biomaterials, 20, 45-53. 

Martin RB, Chapman MW, Holmes RE, Sartoris DJ, Shots EC, Gordon JE, et al. Effects of bone ingrowth on the strength and non-invasive assessment of a coralline hydroxyapatite material. Biomaterials 1989 10 481-488. 

Biocompatibility of materials— biomaterials —in contact with cells or tissue, relies on specific molecular recognition processes, especially at the interfaces. Imprinted surfaces are expected to play a key role in this field in the future [114]. Ultrathin or thin MIP layers for recognition of proteins, but also for cell-specific recognition based on surface-marker structures or cell shape could be envisioned. 

Professor Eugenia Kumacheva is a Canada Research Chair in Advanced Polymer Materials. Her current research interests are in polymer micro- and nanostructured materials, hybrid materials, biomaterials, inorganic nanoscale materials, and microfluidics. 

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