Mass androgenes

Mallet, A. I., Holland, K. T., Rennie, P. J., Watkins, W. J. and Gower, D. B. (1991) Applications of gas chromatography-mass spectrometry in the study of androgen and odorous 16-androstene metabolism by human axillary bacteria. J. Chromatogr-Biomed. 562, 647-658. 

Dehennin L, Ferry M, Lafarge P, Peres G, Lafarge J-P. 1998. Oral administration of dehydroepiandrosterone to healthy men alteration of the urinary androgen profile and consequences for the detection of abuse in sport by gas chro-matography-mass spectrometry. Steroids 63 80-87. 

The absence of appropriate androgen signaling in patients with SMA diminishes protein synthesis, especially in muscle, contributing to decreased muscle mass. The product normally encoded by the SMA gene would best be described as a... 

A number of studies were conducted in order to try and create a drug with high-androgenic and low-anabolic potential however, most attempts were unsuccessful. Because they are structurally similar to testosterone, they exhibit both androgenic and anabolic activity, and are frequently used by athletes for building up muscle mass. At the same time, all of the anabolics currently used have androgenic activity. 

Anabolic steroids have been promoted as a means to foster protein synthesis and inhibit catabolism. Possibilities for considerable weight gain have been implied. In practice however these effects are disappointing, certainly in relation to the toxicity of these agents. In HIV-infected patients the administration of anabolic steroids appeared to result in a small increase in both lean body mass and body weight. The androgenic properties that all anabolic steroids have in common stand in the way of their therapeutic use. 

Androgen production falls with age in men and may contribute to the decline in muscle mass, strength, and libido. Preliminary studies of androgen replacement in aging males with low androgen levels show an increase in lean body mass and hematocrit and a decrease in bone turnover. Longer studies will be required to assess the usefulness of this therapy. 

Rationally, 5/3-reduclase deficiency would not be a cause of MPH, but it seems appropriate to place this disorder adjacent to its 5a-counterpart. 5/3-Reductase (AKR1D1) is an essential bile-acid biosynthetic enzyme and patients with disabling mutations in this enzyme have a clinical phenotype associated with cholestasis and fiver failure. In addition to its importance in bile-acid synthesis, this aldoketo-reductase is responsible for reducing approximately two-thirds of the mass of synthesized androgens, corticosteroids, and aldosterone prior to their excretion, so has a vital role in steroid metabolism. 

In sufficient doses, androgens can alter regional fat distribution, with a reduction in subcutaneous fat despite their body-building effects they have therefore been used as part of slimming programs in men (43). In women, testosterone causes an increase in lean body mass with a reduction in total body fat (44). 

Many athletes who have used high aromatizing AAS have reported a delayed period of HPTA regeneration. As such post-cycle lean mass tissue retention suffers as a negative reaction to suppressed endogenous androgen production. If the boy s are shrunken so is the athlete they are attached to. 

Oxandrolone was reported to stack well with so -called mass steroids such as testosterone or with high anabolic/moderate androgenic steroids such as Equipoise or Nandrolones. Persons over 40 have reported excellent results by stacking 15-25 mg of Oxandrolone daily with 200-400 mg of Deca. 

Those who have read the second book in this series know that the excessive HPTA function inhibition and post-cycle lean mass tissue loss was mostly avoided with Max Androgen Phases, Tide-Cycles, Cortisol/Estrogen Suppression Phases, Absolute Anabolic Phases, and others. See "Building The Perfect Beast" Featuring "Frank N. Steroid" for more info. 

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