Marburg disease

Nlaiburg virus Marburg disease None None... 

The occurrence of laboratory-acquired infections in research workers is not the only problem in biosafety. The other major concern is the potential for release of infectious agents that may cause secondary infections in nonlaboratory workers and other contacts. Fortunately, the potential for such serious outbreaks of laboratory-acquired disease seems to be small. Data derived from studies at the U.S. Department of Agriculture National Animal Disease Center showed that, during the years from 1960 to 1975, no instances of secondary infection in other laboratory workers or in nonlaboratory contacts occurred as the result of the laboratory-acquired infections of 18 research workers who used animal pathogens that were also infective for humans (448). However, the potential for outbreaks of laboratory-associated disease does exist as there are reports in the literature of instances of secondary transmission of laboratory-acquired Marburg disease (283), Q fever (38), and smallpox (105,518). Fortunately, the low level of occurrence of such incidents suggests that... 

Peters, C.J. Marburg and Ebola virus hemorrhagic fevers. In Mandell, G.L., Bennett, J.E., Dolin, R., eds. Principles and practice of infectious diseases. 5th ed. New York, New York Churchill Livingstone 2000, 2, 1821-3. 

K. M., Killey, M., Bagshawe, A., Siongok, T., Keruga, W.K. Marburg-virus disease in Kenia. Lancet 1982 816-820... 

Johnson, K.M. 1990. Marburg and Ebola Viruses. In Principles and Practice of Infectious Diseases, 3rd Ed. New York Churchill Livingstone, pp. 1303-1306. 

Ebola, Lassa, Machupo, and Marburg are some of the 18 different viruses that cause viral hemorrhagic fever (VHP) in humans and other primates that are classified as Category A biological threat agents (CDC 2007). Ebola is a zoonotic disease of primates and occasionally spreads to human populations that are exposed to these animals (Murray et al. 2005). 

Laboratory Centre For Disease Control, Office of Biosafety, Material Safety Data Sheet-Infectious Substances Marburg virus, Minister of National Health and Welfare, Canada, September 1996. 

The rest of this chapter will show how the most successful treatment modalities have developed. These include vaccination (for smallpox, polio, measles, etc.), and chemotherapy using anti-viral drugs. A large number of viral diseases still lack an effective means of treatment, and the chapter will also cover the attempts to treat the common cold and influenza the struggles with HIV and the emergence of viruses (Marburg, Ebola, Lassa) that cause haemorrhagic fever. 

In the section on infectious diseases, which considered Marburg, Ebola and Lassa fever, the conclusion was reached that there are no current technical reasons for regarding these diseases as posing a new biological warfare threat and as far as biocontrol was concerned, the paper again had an optimistic perspective ... 

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