Marburg virus disease

K. M., Killey, M., Bagshawe, A., Siongok, T., Keruga, W.K. Marburg-virus disease in Kenia. Lancet 1982 816-820... 

Martini GA, Siegert R, eds. Marburg Virus Disease. New York, NY Springer-Verlag 1971. 

Laboratory Centre For Disease Control, Office of Biosafety, Material Safety Data Sheet-Infectious Substances Marburg virus, Minister of National Health and Welfare, Canada, September 1996. 

Filoviruses belong to a virus family called Filoviridae and can cause severe hemorrhagic fever in humans and nonliuinan primates. So far, only two members of this virus family have been identified Marburg virus and Ebola virus. Four species of Ebola virus have been identified Ivory Coast, Sudan, Zaire, and Reston. Ebola-Reston is the only known filovirus that does not cau.se severe disease in humans however, it can be fatal in monkeys. 

Just how the animal host first transmits Marburg virus to humans is unknown. However, as with some other viruses which cau.se viral hemorrhagic fever, humans who become ill with Marburg hemorrhagic fever may spread the virus to other people. This may happen in several ways. Persons who have handled infected monkeys and have come in direct contact with their fluids or cell cultures, have become infected. Spread of the virus between humans has occurred in a setting of close contact, often in a hospital. Droplets of body fluids, or direct contact with persons, equipment, or ocher objects contaminated with infectious blood or tissues are all highly suspect as sources of disease. 

Cause severe human disease, serious hazard, high risk of spreading to the community, no effective prophylaxis or treatment usually available Ebola-, lassa-, marburg-viruses... 

Fiiovirus A filamentous virus that displays unusual variability in shape. Two filo-viruses, the Ebola virus and the Marburg virus, have been associated with human disease. 

Martini, G.A. and H.A. Schmidt. 1968. Sper-matogenic transmission of the Marburg virus. (Causes of Marburg simian disease. ) Klin. Wochenschr. 46 396-400. (In German.)... 

Peters, C.J. Marburg and Ebola virus hemorrhagic fevers. In Mandell, G.L., Bennett, J.E., Dolin, R., eds. Principles and practice of infectious diseases. 5th ed. New York, New York Churchill Livingstone 2000, 2, 1821-3. 

Nlaiburg virus Marburg disease None None... 

Johnson, K.M. 1990. Marburg and Ebola Viruses. In Principles and Practice of Infectious Diseases, 3rd Ed. New York Churchill Livingstone, pp. 1303-1306. 

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