Lymphoma immunological

Goates JJ, Kamel OW, LeBrun DP, et al. Floral variant of follicular lymphoma. Immunological and molecular smdies support a neoplastic process. Am J Surg Pathol. 1994 18(l) 37-47. 

Christ, M., Luu, B., Mejia, J.E., Moosbmgger, I., and Bischoff, P., 1993, Apoptosis induced by oxysterols in murine lymphoma cells and in normal thymocytes. Immunology 78 455-460. 

B12. Burkitt, D., Clinical evidence suggesting the development of an immunological response against African lymphoma. Union Int. Contre Cancer Monogr. Ser. 8, 94-103 (1967). 

K2. Klein, G., Immunological aspects of Burkitt s lymphoma. Adean. Immunol. 14, 187-250 (1968). 

Immunological Injury. Defects in immunological function may be manifested by such conditions as recurrent infection, autoimmune disease, and lymphoma (129). It is hypothesized that heavy metals may alter the function of sulfur-rich immunoproteins by displacing trace element cofactors (96). Lead burdens in mice, rats, and baboons similar to those... 

Radiolabeling and the Analysis of Thy-1 Active Glycolipids. The amount of Thy-1 active glycolipids in brain, thymocytes or lymphoma cells was found to be extremely small and could only be detected by immunological methods and not by chemical means. 

C9. Cerroni, L., Rieger, E., Hodl, S., and Kerl, H., Clinicopathologic and immunologic features associated with transformation of mycosis fungoides to large-cell lymphoma. Am. J. Surg. Pathol. 16, 543-552 (1992). 

H8. Harada, S., Suzuki, R., Uehira, K., Yatabe, Y., Kagami, Y., Ogura, M., Suzuki, H., Oyama, A., Kodera, Y., Ueda, R., Morishima, Y., Nakamura, S., and Seto, M., Molecular and immunological dissection of diffuse large B cell lymphoma CD5+, and CD5— with CD10+ groups may constitute clinically relevant subtypes. Leukemia 13, 1441—1447 (1999). 

P10. Pinkus, G. S., O Hara, C. J., and Said, J. W., Peripheral/post-thymic T-cell lymphomas A spectrum of disease. Clinical, pathologic, and immunologic features of 78 cases. Cancer 65,... 

Gross, R.L. et al., In vitro immunological studies on East African cancer patients. II. Increased sensitivity of blood lymphocytes from untreated Burkitt lymphoma patients to inhibition of spontaneous rosette formation, Int. J. Cancer, 15, 132, 1975. 

Immunological rejection following transplantation 10. Malignant lymphoma... 

One boy who had been immunized shortly after birth developed ipsilateral axillary lymphoma at the age of 6 months. Microscopically the picture was typical of BCG histiocytosis. The child survived. The underlying immunological disturbance was considered to be a temporary derangement of T lymphocyte function (SEDA-8, 300) (85). 

Corticosteroids are widely used throughout medical practice. In cancer therapy, prednisone and dexamethasone are the most frequently used. They have a lytic effect on lymphoma and myeloma cells, reduce the edema associated with brain metastases, reduce immunological and allergic reactions and exert an antiemetic effect alone and with 5-HT3 blockers. The many side effects of corticosteroids are often the consequence of the desired effect on the disease process being treated also impacting the normal tissues adversely. These toxicities are well known as they are seen throughout clinical medicine. 

F12. Fudenberg, H. H., Immunologic deficiency, autoimmune disease, and lymphoma observations, implications and speculations. Arthritis Rheum. 9, 464-472 (1966). 

Another situation favoring selection of dormant tumor cells occurs in immunodeficiency states. Spontaneous or induced immunodeficiency often increases susceptibility to neoplasia (Kl, M3). However, the results show more variability than can be explained simply by impairment of immunologic surveillance (M3). In humans the excess is largely due to an increase in the frequency of leukemias and lymphomas, except in those immunodeficiency states associated with chromosomal fragility, such as ataxia telangiectasia (P2, S10). 

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