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Lymphocyte immunophenotyping

IL-2 is the specific pattern of lymphocytes T helper 1 that increases the proliferation of T cells and activates B cells. IL-10 is a specific pattern of lymphocytes T helper 2, which is stimulatory towards certain T cells, mast cells and B cells and inhibits the synthesis of other cytokines produced by Thl. IL-10 was synthesized by cells with higher metabolic rates with respect to IL-2, suggesting a prevalent differentiation in lymphocyte immunophenotype Th2. [Pg.440]

Costantini A, Mancini S, Giuliodoro S et al (2003) Effects of cryopreservation on lymphocyte immunophenotype and function. J Immunol Methods 278 145-155... [Pg.42]

HISTORICAL PERSPECTIVE ON THE USE OF LYMPHOCYTE IMMUNOPHENOTYPING IN IMMUNOTOXICITY RISK ASSESSMENT FOR PHARMACEUTICALS... [Pg.104]

CONSIDERATIONS AND TIMING FOR INCLUSION OF LYMPHOCYTE IMMUNOPHENOTYPING IN THE RISK... [Pg.105]

Incorporation of Immunophenotyping into Standard Toxicity Studies. Lymphocyte immunophenotyping can be performed as part of the standard toxicity... [Pg.107]

Incorporation of Immunophenotyping into Immunotoxicity Studies. In cases where the standard toxicity studies indicate there may be effects on the immune system, lymphocyte immunophenotyping can be incorporated into an immunotoxicity study (Roth et al., 2006). This approach has been studied in... [Pg.109]

A weight-of-evidence approach should be used when evaluating lymphocyte immunophenotyping data to determine the biological and/or toxicological relevance for observed changes. The following questions should be addressed ... [Pg.114]

RELEVANCE OF LYMPHOCYTE IMMUNOPHENOTYPING PBSDINGS IN PRECLINICAL ANIMAL STUDIES TO OVERALL HUMAN RISK ASSESSMENT... [Pg.114]

TABLE 92-3. Morphologic (FAB) Classification and Immunophenotype of Acute Lymphocytic Leukemia... [Pg.1400]

Immunophenotyping Phagocytosis Respiratory burst NK cell activity Lymphocyte proliferation CD45R expression IL-2R expression 62-integrin Immunoglobulins Cytokines Immunogenetics... [Pg.410]

Schwartz, J. et al., The development of methods for immunophenotypic and lymphocyte function analyses for assessment of Southern sea otter (Enhydra lutris nereis) health, Vet. Immunol. Immunopathol., 104, 1, 2005. [Pg.417]

B cell neoplasms based on morphology, immunophenotype, and genotype often, but not always, correspond to stages of B cell development. However, some B cell lymphomas either do not clearly correspond to a specific developmental stage (i.e., appear to be of variable origin such as chronic lymphocytic leukemia/small lymphocytic lymphoma) or do not appear to be related to any known stage of normal development (i.e., hairy cell leukemia) (H10). [Pg.309]

F9. Felgar, R. E., Salhany, K. E., Macon, W. R., Pietra, G. G., and Kinney, M. C., The expression of TIA-1 + cytolytic-type granules and other cytolytic lymphocyte-associated in CD30+ anaplastic large cell lymphomas (ALCL) Correlation with morphology, immunophenotype, ultrastructure, and clinical features. Hum. Pathol. 30, 228—236 (1999). [Pg.336]

K8. Kilo, M. N., and Dorfman, D. M., The utility of flow cytometric immunophenotypic analysis in the distinction of small lymphocytic lymphoma/chronic lymphocytic leukemia from mantle cell lymphoma. Am. J. Clin. Pathol. 105, 451—457 (1996). [Pg.340]

M16. Matutes, E., Morilla, R., Owusu-Ankomah, K., Houliham, A., Meeus, R, and Catovsky, D., The immunophenotype of hairy cell leukemia (HCL). Proposal for a scoring system to distinguish HCL from B-cell disorders with hairy or villous lymphocytes . Leuk. Lymphoma 14, 57-61 (1994). [Pg.344]

Ml8. Matutes, E., and Polliack, A., Morphological and immunophenotypic features of chronic lymphocytic leukemia. Rev. Clin. Exp. Hematol. 4, 22-47 (2000). [Pg.344]

Pranzatelli MR, Travelstead AL, Tate ED, Allison TJ, Moticka EJ, Franz DN, et al. B- and T-cell markers in opsoclonus-myoclonus syndrome Immunophenotyping of CSF lymphocytes. Neurology 2004 62(9) 1526—1532. [Pg.176]

Immune system Hematology/clinical chemistry Organ weights Histopathology Antibodies Imm unoglobulins Immunophenotyping NK cell activity" Lymphocyte proliferation TDAR and DTH CD immunohistochemistry of lymphatic organs Cytokines... [Pg.384]

Loken, M. R., Brosnan, J M., Bach, B. A., and Ault, K. A (1990) Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry Cytometry... [Pg.224]

Weisenburger DD, Sanger WG, Armitage JO, Purtilo DT. Intermediate lymphocytic lymphoma immunophenotypic and cytogenetic findings. Blood 1987 69 1617-21. [Pg.1481]


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See also in sourсe #XX -- [ Pg.107 , Pg.110 ]




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