Lung damage

Activated alumina is a relatively innocuous material from a health and safety standpoint. It is nonflammable and nontoxic. Fine dusts can cause eye irritation and there is some record of lung damage because of inhalation of activated alumina dust mixed with siUca [7631-86-9] and iron oxide [1317-61 -9] (30). Normal precautions associated with handling of nuisance dusts should be taken. Activated alumina is normally shipped in moisture-proof containers (bags, dmms, sling bins) because of its strong desiccating action. 

Bromothiophenes are toxic materials by aU routes. Inhalation toxicity of 2-bromothiophene is significant. Ecotoxicity is also noted for these materials, particularly for 2-bromo-3-methylthiophene. 2-Thiophenecarboxaldehyde and the 3-methyl derivative can cause minor irritation to the skin and eyes of rabbits. The former is a sensitizer to guinea pig skin, the latter is not. 2-Acetylthiophene is toxic in aU modes of contact. Severe exposure causes serious inflammation of the lung, damage to many organs, and depression of the central nervous system. 

Aluminium alkyls Chromic oxide Alkylations/Grignard reactions Acute thermal burns, lung damage Cr may be converted to the more toxic and carcinogenic Cr ... 

Handling hazardous ehemieals has beeome part of most people s everyday living. Just eonsider gasoline, and how most people fill their own tanks. In the manufaeturing arena, ehemieals are eommonplaee. On hazardous waste sites there are a variety of unknown ehemieal substanees and other hazards that may take the form of a solid, liquid, or gas. The eflfeets of exposure to toxie ehemieals may either be immediate (e.g., aeid burns) or delayed (e.g., lung damage from inhaling asbestos). There are four routes of ehemieal exposure that exist ... 

Limit Minor Structural Damage 0.4 T TS Lung Damage Severe 80 up... 

High concns of aluminum oxide dust can cause various types of lung damage such as Shaver s disease, fibrosis, emphysema and pneumothorax Refs 1) Gmelin, Syst Nr 35, Ted B (1934),... 

Other enzyme systems may also be directly or indirectly involved in the generation of ROS in the lung, including those of the eicosanoid pathway, the mitochondrial electron transport system, and aldehyde, glucose and xanthine oxidases (Parks and Granger, 1986). These systems may also be relevant to lung damage. For example, the oedematous pulmonary injury that results from cessation of blood flow for a period followed by reinstatement of... 

Doelman, C.J.A., Leurs, R., Ooestrom, W.C. and Bast, A. (1990). Mineral dust exposure and free radical-mediated lung damage. Exp. Lung Res. 16, 41-55. 

The contributions of QMs to the toxicities of the food additive BHT and structurally related alkylphenols in rats and mice have been investigated extensively over the past 25 years. This work has generated considerable insight into the relationships between toxicity and the metabolic formation and reactivity of these electrophiles. Most studies have focused on liver and lung damage is primarily observed in these organs due,... 

Read the labels before mixing household cleansers. Many toilet-bowl cleaners contain acidic solutions, as do some drain cleaners, rust removers, and, of course, vinegar. Never mix bleach with these products. You could sustain permanent lung damage. 

Of the 16 POPs listed in the 1998 Aarhus Protocol [27], 11 are organochloride pesticides, which have now been banned in several countries. Most concerns regarding these products relate to their toxicity, with health effects to humans ranging from lung damage and neurological problems to death. Many organochloride pesticides are lipophilic, and they accumulate in the adipose tissues. 

The latest studies show that reactive nitrogen species play even more important role in asthma development. It was found that exhaled nitrogen oxide, an indicator of eosinophilic airway inflammation, is drastically enhanced in asthmatic patients. Correspondingly, it has been shown that lung damage is characterized by the augmentation of nitrotyrosine and iNOS expression in neutrophils, eosinophils, and macrophages in the airways of asthmatic patients [266],... 

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