Nitrogen dioxide, lung damage

Some toxic substances such as sulfur dioxide, nitrogen dioxide, and ozone cause acute, direct damage to lung tissue, whereas others, such as nickel carbonyl, may lead to the formation of tumors. 

Nitrogen dioxide 100 (0.05 ppmv) 100 (0.05 ppmv) 1 yr Lung damage, acid rain, and formation of ozone and secondary pollutants... 

There are over 40 different cell types in the respiratory system, and those particularly susceptible are the lining cells of trachea and bronchi, endothelial cells and the interstitial cells (fibroblasts and fibrocytes). Some toxic substances such as sulphur dioxide, nitrogen dioxide and ozone cause acute, direct damage to lung tissue, whereas others, such as nickel carbonyl may lead to the formation of tumours. 

An emphysema-like damage to the lung occurs after chronic exposures to nitrogen dioxide. 

AU three are oxidizing agents. Ozone, sulfur dioxide and nitrogen dioxide cause lung damage. 

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