5-lipoxygenase, genetic

Choi JH, Park HS, Oh HB, et al. (2004) Leukotiiene-related gene polymorphisms in ASA-intolerant asthma an association with a haplotype of 5-lipoxygenase. Hum Genet. 114, 337-344. 

Helgadottir A, Manolescu A, Thorleifsson G, et al. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet. Mar 2004 36(3) 233-239. 

Silverman, E.S., Drazen, J.M. 2000. Genetic variations in the 5-lipoxygenase core promoter. Description and functional implications. Am. J. Respir Crit. Care Med. 161 S77-S80. 

Wang and Johnson (2001) processed normal soybeans and several types of genetically enhanced soybeans with four extraction methods. The genetically enhanced soybeans were high-oleic with 79.2% oleic acid, low saturated fat with 8.4% total saturated fatty acids, low-linolenic with 3.1% linolenic acid, lipoxygenase-free, and an experimental line of high-cysteine soybeans. The fatty acid compositions of some of these soybeans are compared to oil from commodity soybeans (Table 6.6). Comparisons of fatty acids of soybeans to corn oil, canola, and lard are also given in Table... 

Davies, C.S. N.C. Nielsen. Genetic analysis of a null-allele for lipoxygenase-2 in soybean. Crop Sci. 1986,26, 460 63. 

Any of a series of two or more different genes that may occupy the same position or locus on a specific chromosome Arachidonate 5-lipoxygenase gene promoter Apolipoprotein A and Apolipoprotein E Cne of the pairs of chemical bases joined by hydrogen bonds that connect the complementary strands of a DNA molecule or of an RNA molecule that has two strands The genetic constitution of an individual referring to either a gene combination at one specified locus or any specified combination of loci Hepatic lipase... 

A crucial problem in the elucidation of biological functions of plant lipoxygenases is the tremendous genetic heterogeneity of this enzyme family in plants, which surpasses that in mammalian cells. For example, in some cases 10 or more different isoenzymes can be found in the same species of plant. The expression of some isoenzymes appears to be related to defined developmental stages and to certain organs or tissues (see Chapter 8). The present chapter is confined to reviewing some of the basic functions for which ample evidence exists and is best read in conjunction with Chapters 4 and 8. 

Yenofsky RL, Fine M, Liu C. Isolation and characterization of a soybean Glycine max) lipoxygenase-3 gene. Mol Gen Genet 1988 211 215-222. 

Bell E, Mullet JE. Lipoxygenase gene expression is modulated in plants by water deficit, wounding and methyl jasmonate. Mol Gen Genet 1991 230 456-462,... 

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