Lectins reviews

A mechanical device for the continuous purification of biological material using an immunoadsorbent has been described.The use of immobilized lectins in affinity chromatography has been discussed,and the purification of cell-membrane glycoproteins on columns of immobilized lectins reviewed. New teehniques of cell fractionation involving use of immobilized lectins or selective agglutination with leetins have been described. ... 

A third area of development in carbohydrate l.c. analyses is in the combined techniques (see Section IV,3) and other methods that provide qualitative, as well as quantitative, information about sample constituents, such as high-performance liquid affinity chromatography. The use of specific lectin- and monoclonal antibody-based, stationary phases for analytical and preparative applications is now being considered. The basic concepts of these techniques have been reviewed - and their applications to carbohydrates have been discussed. 

Cell division is stimulated by lectins (for a review, see Ref. 188) and by other saccharide-directed reagents, for example, sodium periodate and D-galactose oxidase after desialylation,189 but there is no evidence that it is the fucopyranosyl residues that are the specific receptors in these instances. The L-fucose-specific lectins from, for example, Lotus tetragonolobus and Ulex europeus are not mitogenic. 

A review of the genomic evidence for the conservation of the galectins, a family of lectins. 

Introduction to a series of excellent reviews on lectins and their biological roles, all published in this issue. 

Lectins are carbohydrate-binding proteins that have been obtained mainly from plants,1128,138 although lectin-like proteins have also been found in micro-organisms and animals,139 including mammals.140 141 Some of the properties of the lectins, and their utility as carbohydrate-specific reagents have been reviewed.1128,138,138... 

In this Section will be discussed plant lectins that specifically bind to a-D-galactopyranosyl residues. Lectins of a special class that are specific for j8-D-glycosidic linkages487 also exist in the seeds and other tissues of plants. Various aspects of lectins have been reviewed by Goldstein and Hayes.488... 

Recent reviews pertaining to such topics as the role of calcium in growth control (82), lectins as natural membrane components (83), fibronectins (84), and biochemical studies of the cell cycle (85, 86, 87, 88), together with many of the works cited earlier, suggest a dynamic, time-dependent relationship between extracellular factors, membrane components and the intracellular metabolic machinery as a cell goes from... 

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