Lectins lectin-like receptors

Hikami K, Tsuchiya N, Yabe T, Tokunaga K. Variations of human killer cell lectin-like receptors common occurrence of NKG2-C deletion in the general population. Genes Immun 2003 4(2) 160-167. 

In the context of dmg delivery, certain cell surface receptor and ion-channel families are particularly appealing as dmg delivery targets. Well-characterized examples include the lectin-like receptor gene family as receptors for glycosylated molecules, as well as vitamin- and trace element-uptake systems such as the transferrin-receptor. 

Ly49 killer cell lectin-like receptor subfamily A, member 1. Analogous for human KIRs. A natural killer cell receptor. 

Jungery, M., Pasvol, G., Newbold, C. I., and Weatherall, D. J. (1983). A lectin-like receptor is involved in invasion of erythrocytes by Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 80,1018-1022. 

A. Cambi, C.G. Figdor, Dual function of C-type lectin-like receptors in the immune system, Curr. Opin. Cell Biol. 2003, 15, 539-546. 

In contrast to the lectin-like receptors on mouse NK cells, a large immunoglobulin superfamily (now termed killer immunoglobulin-like receptors , or KIRs) has been identified and its members characterised for their ability to regulate human NK cell functions. Comprising either two or three extracellular... 

C-Type Lectin-Like Receptors and Effects of Binding by Fungal PAMPs... 

Douglas SD (2001) Methadone may promote HIV replication study. AIDS Alert 16 120 Dreyer EB, Kaiser PK, Offermann IT, Lipton SA (1990) HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science 248 364-367 Dunn S, Vohra RS, Murphy JE, Homer-Vanniasinkam S, Walker JH, Ponnambalam S (2008) The lectin-like oxidized low-density-lipoprotein receptor a pro-inflammatory factor in vascular disease. Biochem J 409 349-355... 

Oka, K., Sawamura, T, Kikuta, K., Itokawa, S., Kume, N., Kita, T, and Masaki, T, 1999, Lectin-like low-density lipoprotein receptor 1 mediates phgocytosis of aged/apoptic ceUs in endothelial ceUs, Proc. Natl. Acad. Sci. U.S.A. 96 6353-6358. 

The selectins are a family of vascular cell surface receptors that are characterized by lectin-like domains at their amino termini, an adjacent epidermal growth factorlike domain, followed by multiple, short consensus repeat units homologous to those of the complement regulatory proteins. Platelet express P-selectin (CD62 ... 

K. Hayashida, N. Kume, M. Minami and T. Kita, Lectin-like oxidized LDL receptor-1 (LOX-1) supports adhesion of mononuclear leukocytes and a monocyte-like cell line THP-1 cells under static and flow conditions, FEBS Lett. 511 (2002) 133-138. 

Hussain N, Jani PU, Florence AT (1997) Enhanced Oral Uptake of Tomato Lectin-Conjugated Nanoparticles in the Rat. Pharm Res 14(5) 613-618 Jackson DC, Lau YF, Le T, Suhrbier A, Deliyannis G, Cheers C, Smith C, Zeng W, Brown LE (2004) A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses. Proc Natl Acad Sci U S A 101(43) 15440-15445... 

Drickamer, K. (1999). C-type lectin-like domains. Curr. Opin. Struct. Biol. 9(5), 585—590. Farag, S. S., Fehniger, T. A., Ruggeri, L., Velardi, A., and Caligiuri, M. A. (2002). Natural killer cell receptors New biology and insights into the graft-versus-leuke-mia effect. Blood 100(6), 1935-1947. 

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