Lamotrigine Oxcarbazepine

U.K. guidelines Carbamazepine Lamotrigine Oxcarbazepine Topiramate Valproic acid ... [Pg.594]

U.S. Expert Panel 2005 Carbamazepine Lamotrigine Oxcarbazepine Levetiracetam ... [Pg.594]

U.K. guidelines Tiagabine Topiramate Zonisamide Children Gabapentin Lamotrigine Oxcarbazepine Topiramate Gabapentin ... [Pg.595]

U.S. Expert Panel 2005 Valproic acid Carbamazepine Lamotrigine Oxcarbazepine Phenobarbital Phenytoin Topiramate Valproic acid Children Carbamazepine Phenobarbital Phenytoin Topiramate Valproic acid Lamotrigine... [Pg.595]

After first trimester carbamazepine, lamotrigine, oxcarbazepine, or valproate Second choice benzodiazepine (lorazepam) Third choice calcium channel blocker With psychosis first choice adjunctive high-potency typical antipsychotic (haloperidol, perphenazine, thiothixene, or trifluoperazine)... [Pg.1269]

Extracted carbamazepine, carbameizepine epoxide, hydro carbamazepine, lamotrigine, oxcarbazepine, phenobarbital Also analyzed ibuprofen, naproxen, trimethoprim... [Pg.1119]

Therefore, plasma concentrations for drugs metabolized by these isoforms will be affected (see Chapter 10). Thus, the addition of phenytoin to an AED regimen can reduce their plasma levels by inducing their CYP3A4 metabolism for carbamazepine, felbamate, lamotrigine, oxcarbazepine, tiagabine, valproate, and zonisamide. Other drugs for which metabolism is induced by phenytoin include methadone, theophylline, warfarin, and oral contraceptives. On the other hand, plasma phenytoin levels are increased by carbamazepine, felbamate, cimetidine, warfarin, chloramphenicol, isoniazid, and disulfiram. Plasma phenytoin levels are decreased by rifampin, antacids, and valproate (free phenytoin levels remain the same). [Pg.774]

Carbamazepine, felbamate, lamotrigine, oxcarbazepine, phenytoin, topiramate, zonisamide... [Pg.293]

Antipsychotics, bromocriptine, carbamazepine, chlorpropamide, cyclophosphamide, desmopressin, ecstasy, lamotrigine, monamine oxidase inhibitors, NSAIDs, oxcarbazepine, oxytocin, tricyclic antidepressants, selective serotonin reuptake inhibitors, vasopressin, vinblastine, and vincristine... [Pg.169]

Depression is a common problem in patients with epilepsy, with approximately 30% having symptoms of major depression at some point.34 Patients with epilepsy should be routinely assessed for signs of depression, and treatment should be initiated if necessary. Certain AEDs may exacerbate depression, for example levetirac-etam and phenytoin. Other AEDs (e.g., lamotrigine, carba-mazepine, and oxcarbazepine) maybe useful in treating depression. Changes in mood can be precipitated by addition or discontinuation of an AED. If treatment for depression is necessary, caution should be exercised in choosing an agent that does not increase seizure frequency and does not interact with AEDs. [Pg.457]

First, two-drug combinations lithium3 or lamotrigine6 plus an antidepressant8 lithium plus lamotrigine Alternative anticonvulsants carbamazepine, oxcarbazepine, or valproate... [Pg.591]

Pharmacotherapy is the cornerstone of acute and maintenance treatment of bipolar disorder. Mood-stabilizing drugs are the usual first-choice treatments and include lithium, divalproex, carbamazepine, and lamotrigine. Atypical antipsychotics other than clozapine are also approved for treatment of acute mania. Lithium, lamotrigine, olanzapine, and aripiprazole are approved for maintenance therapy. Drugs used with less research support and without Food and Drug Administration (FDA) approval include topiramate and oxcarbazepine. Benzodiazepines are used adjunctively for mania. [Pg.592]

Lithium Carbamazepine Oxcarbazepine Divalproex (DVPX) Sodium/Valproic Acid (VPA) Lamotrigine... [Pg.595]

Lamotrigine Levetiracetam Oxcarbazepine Tiagabine Topiramate Generalized seizures absence (newly diagnosed) ... [Pg.595]

Studies suggest that as monotherapy for partial seizures, lamotrigine is as effective as carbamazepine and phenytoin lamotrigine may be better tolerated. Clinical data suggest that oxcarbazepine is as effective as phenytoin, valproic acid, and immediate-release carbamazepine, with perhaps fewer side effects. [Pg.599]

The newer AEDs were first approved as adjunctive therapy for patients with refractory partial seizures. To date, lamotrigine, topiramate, and oxcarbazepine have received FDA approval for use in monotherapy in patients with partial seizures. Felbamate has monotherapy approval but causes significant side effects. [Pg.599]

Other anticonvulsants snch as oxcarbazepine, gabapentin, and lamotrigine may also be helpful in treating the affective lability and impulsivity seen in BPD, though little data is available. Each of these medications is discussed in Chapter 3. [Pg.328]

Vigabatrin (irreversible GABA aminotransferase inhibitor), zonisamide, lamotrigine (217) (glutamate inhibitor), oxcarbazepine (218), levetiracetam (219), piracetam, tiagabine (220),... [Pg.69]

Drugs that may be affected by oxcarbazepine include felodipine, lamotrigine, oral... [Pg.1277]

Type I Block SRF by enhancing sodium channel inactivation Phenytoin Carbamazepine Oxcarbazepine Lamotrigine Felbamate ... [Pg.376]

Another group of mood-stabilizing drugs that are also anticonvulsant agents have become more widely used than lithium. These include carbamazepine and valproic acid for the treatment of acute mania and for prevention of its recurrence. Lamotrigine is approved for prevention of recurrence. Gabapentin, oxcarbazepine, and topiramate are sometimes used to treat bipolar disorder but are not approved by FDA for this indication. Aripiprazole, chlorpromazine, olanzapine, quetiapine, risperidone, and ziprasidone are approved by FDA for the treatment of manic phase of bipolar disorder. Olanzapine plus fluoxetine in combination and quetiapine are approved for the treatment of bipolar depression. [Pg.638]

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