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Anticonvulsant carbamazepine

Mr. Parks, age 32 years, has recently received a diagnosis of epilepsy. He has been taking the anticonvulsant carbamazepine, but his seizures are not yet under control. Mr. Parks asks you how long it will take to cure his epilepsy. Determine how you would respond to Mr. Parks. [Pg.263]

Anticonvulsants Carbamazepine, valproic acid, gabapentin, topiramate... [Pg.135]

First, initiate and/or optimize mood-stabilizing medication lithium3 or lamotrigine6 Alternative anticonvulsants carbamazepine, oxcarbazepine, or valproate... [Pg.591]

Anticonvulsants (carbamazepine, Increase metabolism of COCs via induction of various Decrease efficacy of OCs (EE doses less... [Pg.746]

Anticonvulsants. Carbamazepine and, to a lesser extent, valproic acid have been tried in attempts to reduce craving by interfering with kindling as well. Initial pilot studies were positive but more recent results have been unimpressive. [Pg.198]

Anticonvulsant Carbamazepine, ethosuximide, lamotrigine, mesantoin, phenytoin, trimefhadione, valproic acid... [Pg.416]

Anticonvulsant Carbamazepine Valproic acid 200-1000 mg/day 125-1750 mg/day Cluster B and C symptoms Cluster B and D symptoms... [Pg.586]

Figure 1.15 The Butterfly Angle . Tricyclic drugs consist of anticonvulsants (carbamazepine), antidepressants (amitriptyline), and antipsychotics (chlorpromazine). Although aU three families consist of three interconnected ring systems, the orientation between the rings varies, imparting a different spectrum of bioactivity. Figure 1.15 The Butterfly Angle . Tricyclic drugs consist of anticonvulsants (carbamazepine), antidepressants (amitriptyline), and antipsychotics (chlorpromazine). Although aU three families consist of three interconnected ring systems, the orientation between the rings varies, imparting a different spectrum of bioactivity.
Post RM, Berrettini W, Uhde TW. Selective response to the anticonvulsant carbamazepine in manic-depressive illness a case study. J Clin Psychopharmacol 1984 4 178-185. [Pg.221]

Among the recently evaluated treatments for BZD withdrawal are anticonvulsants (carbamazepine and VPA) ( 256), melatonin (257), and ondansetron (258). Of these, odansetron had no significant effects on severity of withdrawal symptoms melatonin was found to effectively facilitate discontinuation of BZD therapy while maintaining good sleep and carbamazepine and VPA may be beneficial in the management of BZD discontinuation but not in decreasing the severity of BZD withdrawal (259, 260). [Pg.247]

For patients with bipolar affective disorder (manic-depressive illness) lithium, usually in the form of lithium carbonate, has been the main prophylactic agent for the last forty years. However, during the last ten years certain anticonvulsants (carbamazepine and sodium valproate) have also been found to be effective. [Pg.179]

Carbamazepine. The anticonvulsant carbamazepine was actually the first to be shown to be effective in the manic phase of bipolar disorder, but it has not been approved for this use by regulatory authorities such as the U.S. Food and Drug Administration (FDA). Its mechanism of action may be to enhance GABA function, perhaps in part by actions on sodium and/or potassium channels (Fig. 7—24). Because its efficacy is less well documented and its side effects can include sedation and hematological abnormalities, it is not as well accepted for first-line use in the treatment of mood disorders as either lithium or valproic acid. [Pg.269]

There is little evidence that lithium is superior to other drugs with sedative actions for the treatment of acute mania. Benzodiazepines, neuroleptics and anticonvulsants have all been tried in mania and none have been found to be inferior to lithium. Two small studies of clonazepam in mania found it was superior to lithium (Chouinard 1988 Chouinard, Young, Annable 1983). All new- and old-generation neuroleptics have been found to be more effective than placebo (Perlis et al. 2006). Comparisons of lithium with the sedative anticonvulsants carbamazepine and sodium valproate show similar effects (Bowden et al. 1994 Freeman et al. 1992 Lerer et al. 1987 Small et al. 1991). [Pg.189]

Other mood stabilizing anticonvulsants (carbamazepine, oxcarbazepine, lamotrigine)... [Pg.8]

Anticonvulsants. Carbamazepine, phenobarbital and primidone accelerate warfarin metabolism (enzyme induction) the effect of phenytoin is variable. Clonazepam and sodium valproate are safe. [Pg.572]

Two anticonvulsants, carbamazepine (Tegretol) and valproic acid, also referred to as valproate (Depakote, Depakene), have proven mood-stabilizing properties (see figure 15-E). These agents are most useful when lithium is contraindicated or when a patient does not respond to or cannot tolerate lithium. Rapid cyclers, who often are poorly controlled with lithium, are good candidates for one of these alternative agents. Valproic acid appears to be indicated more for manic or mixed states of bipolar disorder, and is probably not as effective in depressed states. The anticonvulsants are often employed in conjunction with lithium. [Pg.164]


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See also in sourсe #XX -- [ Pg.291 ]




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