Label instructions

Copies of labels, instructions for use or user manuals or other relevant information Comparative information... 

Pharmaceutical scientists have developed improved suspension dosage forms to overcome problems of poor physical stability and patient-perceived discomfort attributed to some active ingredients. An important development aspect of any suspension is the ability to resuspend easily any settled particles prior to instillation in the eye and ensure that a uniform dose is delivered. It would be ideal to formulate a suspension that does not settle since the patient may not always follow the labeled instructions to shake well before using. However, this is usually not feasible or desirable since the viscosity required to retard settling of the insoluble particles completely would likely be excessive for a liquid eyedrop. The opposite extreme, of allowing complete settling between doses, usually leads to a dense layer of agglomerated particles that are difficult to resuspend. 

Definition of measures for reducing exposure label instructions.116... 

Minimum label instruction according to point 1 for all plant protection products applied as a liquid... 

See Figure 1.) If re-entry into certain crops, regularly or occasionally, cannot be excluded, but a "worst-case" risk assessment shows that exposure remains below the tolerable level even without specific skin protection measures, it will be sufficient to include the minimum label instruction, point 1 ... 

The inclusion of the minimum label instruction might also be considered as a matter of general working hygiene for all products for which application leads to wetting of the plant surface. 

Zerit (stavudine) for oral solution is supplied as a dye-free, fruit-flavored powder in bottles with child-resistant closures providing 200 mL a 1 mg/mL stavudine solution on constitution with water per label instructions. 

Failure to abide by the approved label instructions is by far the leading cause of illegal residues detected in edible animal products. Noncompliance with proper withdrawal periods was responsible for 46% and 54% of the cases of violative residues monitored in the fiscal years 1990 and 1991, respectively, in the United States. Failure to comply with approved withdrawal periods was also identified as the most common cause of the drug violations monitored in the fiscal year 1993 by the Food Safety and Inspection Service of the Food and Drug Administration (FDA). Livestock species producing most violations were the bob veals, with approximately 40%, followed by cull cows with 30%. 

Apart from noncompliance with approved label instructions, a high percentage of residue violations has also been connected with errors from improperly trained personnel and family members. Residues are not, however, always the personnel s fault. Farmers are also negligent. They rely on memory when it comes to which cows they have treated, or they forget to notify members or other milkers who then milk a treated cow into the tank. Perhaps they mark cows in one manner only the leg band falls off or the chalk wears off. Some producers paint the hind quarters but fail to take the mark off once the cow s milk is clear. An extensive onfarm review based on investigations of 20 cases of antibiotic adulteration in milk representing 797,436 pounds of dumped milk by a major US milk cooperative demonstrated that management mistakes were to blame in all cases. All... 

Xanthene dyes have not exhibited health or safety properties warranting special precautions however, standard chemical labeling instructions are required. 

Health Canada has advised consumers against using some products containing iodine (SEAVITE Premium Atlantic Kelp tablets), since these products, when consumed according to the label instructions, can provide 25 times the recommended daily allowance (RDA) of iodine for adults this could lead to serious adverse health consequences (9). The RDA for iodine ranges from 90... 

Use of Data Obtained When data is received, such as that provided by a study conducted as suggested above, an assessment is made as to the adequacy of label instructions in mitigating any perceived hazards of use. 

Elements [12] to [14] of the prescription include refill information, waiver of the requirement for childproof containers, and additional labeling instructions (eg, warnings such as "may cause drowsiness," "do not drink alcohol"). Pharmacists put the name of the medication on the label unless directed otherwise by the prescriber, and some medications have the name of the drug stamped or imprinted on the tablet or capsule. Pharmacists must place the expiration date for the drug on the label. If the patient or prescriber does not request waiver of childproof containers, the pharmacist or dispenser must place the medication in such a container. Pharmacists may not refill a prescription medication without authorization from the prescriber. Prescribes may grant authorization to renew prescriptions at the time of writing the prescription or over the telephone. Elements [15] to [17] are the prescriber s signature and other identification data. 

Label instructions must be clear and unambiguous and include, where relevant, the intended duration of treatment. 

Have labeling instructions understandable to the average person who will use the product... 

Schedule for medication administration. Patients must be made aware of appropriate intends between drug doses. Timing of administration may affect absorption and blood or ocular levels of the drug. Clinicians should provide verbal definition of label instructions (e g., before meals, after meals, at bedtime two, three, or four times daily every 4,6, or 12 hours on an empty stomach). As directed is considered an inappropriate form of patient instruction. 

The release (other than spills or other accidents) of a pesticide registered under FIFRA when used generally in accordance with its intended purpose (during routine agricultural applications according to approved product label instructions) is exempted from this reporting requirement. 

Table 5.2 shows how signal words can be used to select the appropriate personal protective equipment (PPE) for different toxicity categories. In aU cases follow label instructions. 

Before handlers do any handling task, inform them of all pesticide labeling instructions for safe use. 

Typical pesticide labeling instructions about storage include ... 

Use all the mixed pesticide in accordance with labeling instructions. 

Pesticide wastes are toxic. Improper disposal of excess pesticide is a violation of Federal law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental... 

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