Ketones ethyl butyl ketone

Animal studies have shown MEK to enhance the development of or increase the severity of neurotoxic effects due to methyl n-butyl ketone, ethyl butyl ketone, -hexane, and 2,5-hexanedione."MEK exposure did not, however, potentiate the neurobehavioral test decrements produced by acetone. Exposure to 200 ppm MEK or 100 ppm MEK plus 12 5 ppm acetone for 4 hours did not produce any significant effects in a variety of behavioral performance tests, whereas exposure to 250 ppm acetone caused some mild decrements. The liver and kidney toxicity of haloalkane solvents may also be potentiated by MEK. ... 

Synonyms Butyl ethyl ketone n-Butyl ethyl ketone Ethyl butyl ketone Ethyl-n-butyl ketone Heptan-3-one... 

Fteptanone, see Methyl amyl ketone 3- Heptanone, see Ethyl butyl ketone ... 

Ethyl butyl ketone, hi5 Ethyl caprate, el20 Ethyl caproate, el60 Ethyl caprylate, e231 Ethyl chloride, cl21... 

Organic solvents inhaled by abusers include gasoline, glue, aerosols, amyl nitrite, butyl nitrite, typewriter correction fluid, lighter fluid, cleaning fluids, paint products, nail polish remover, waxes, and varnishes. Chemicals in these products include nitrous oxide, toluene, benzene, methanol, methylene chloride, acetone, methyl ethyl ketone, methyl butyl ketone, trichloroethylene, and trichloroethane. 

Ethyl sec-amyl ketone, see 5-Methyl-3-heptanone Ethylbenzol, see Ethylbenzene Ethyl butyl ketone, see 3-Heptanone Ethyl n-butyl ketone, see 3-Heptanone Ethyl carbinol, see 1-Propanol Ethyl cellosolve, see 2-Ethoxyethanol Ethyl chloride, see Chloroethane Ethylcyclopentan, see Ethylcyclopentane Ethyldimethylmethane, see 2-Methylbutane Ethylendiamine, see Ethylenediamine Ethylene aldehyde, see Acrolein Ethylene bromide, see Ethylene dibromide Ethylene bromide glycol dibromide, see Ethylene dibromide... 

Toxicology. Ethyl butyl ketone (EBK) is mildly irritating to the skin and eyes of animals and causes narcosis at high concentrations. 

The 2003 ACGIH threshold limit value-time-weighted average (TLV-TWA) for ethyl butyl ketone is 50 ppm (234mg/m ). 

Katz GV et al Comparative neurotoxicity and metabolism of ethyl -butyl ketone and methyl -butyl ketone in rats. Toxicol Appl Pharmacol 52 153-158, 1980... 

Because the aldol reaction is reversible, it is possible to adjust reaction conditions so that the two stereoisomeric aldol products equilibrate. This can be done in the case of lithium enolates by keeping the reaction mixture at room temperature until the product composition reaches equilibrium. This has been done, for example, for the product from the reaction of the enolate of ethyl /-butyl ketone and benzaldehyde. 

Z-Boron enolates can also be obtained from silyl enol ethers. This method is necessary for ketones such as ethyl /-butyl ketone, which gives /i-boron enolates by other methods. The Z-stereoisomer is formed from either the Z- or /r-silyl enol ether.20... 

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