Isopropyl Carbinol

Isobutyl alcohol, isobutanol, 2-methyl-propanol, isopropyl carbinol, Me2CHCH20H. B.p. 108°C. Occurs in fusel-oil. Oxidized by potassium permanganate to 2-methyl-propanoic acid dehydrated by strong sulphuric acid to 2-methylpropene. 

In order to explore the possibility of tuning product stereochemistry by changing the experimental conditions, we carried out the reaction using different secondary alcohols as donor, namely di-isopropyl-carbinol (2,4-dimethyl-2-pentanol), 2-octanol, 3-octanol and cyclohexanol. 

Methyl n-amyl carbinol. 247, 254 Methyl n-amyl ketone, 482 Methylaniline (mono), pure, from commercial methylaniline, 562, 570 P-Methylanthraquinone, 728, 740 Methyl benzoate, 780, 781 p-Methyl benzyl alcohol, 811,812 Methyl benzyl ketone, 727, 735 Methyl y-bromocrotonate, 926, 927 2-Methyl-2-butene, 239 Methyl n-butyl carbinol, 247,255 Methyl n-butyl ether, 314 Methyl n-butyl ketone, 475, 481 4-Methylcarbostyril, 855 p-Methylcinnamic acid, 719 4-Methylcoumarin, 853, 854 Methyl crotonate, 926, 927 Methylethylacetic acid, 354, 358 Methylethylethynyl carbinol, 468 Methyl ethyl ketone, 335, 336 purification of, 172 Methyl n-hexyl ether, 314 Methyl n-hexyl ketone, 335, 336 Methyl n-hexyl ketoxime, 348 Methyl hydrogen adipate, 938 Methyl hydrogen sebacate, 938,939 4-Methyl-7-hydroxycoumarin, 834 Methyl iodide, 287 Methyl isopropyl carbinol, 247,255 Methyl 4-keto-octanoate, 936... 

After addition of the acetaldehyde solution is complete, the product is decomposed by pouring the reaction mixture on to 2 kg. of cracked ice. The excess magnesium may be removed conveniently by decantation at this point. The basic magnesium halide is dissolved by addition of about 11. of 15 per cent sulfuric acid. The ether solution is separated, and the aqueous layer is extracted with four 150-cc. portions of ether. The ether solutions are combined, dried over 25 g. of calcined potassium carbonate, filtered and fractionally distilled, using a short column. The methyl isopropyl carbinol distils at no-ni.50. The fraction boiling 37 -1090 should be dried and refractionated. The total yield is 210-215 g. (53-54 per cent of the theoretical amount) (Note 7). 

Methyl isopropyl carbinol has been prepared by reduction of methyl isopropyl ketone with sodium amalgam,1 and with... 

Methyl ethyl ketone, 10, 23 Methylethyl ketoxime, 11, 59 a Mcthyl-d-glucoside, 10, 112 Methyl isopropyl carbinol, 12, 48 S-METHyLISOTHIQUREA SULPATE, 12, S2... 

B.ll) (B.11) 1-Propanol,2-methyl, 2-methylpropan-l-ol, isobutanol, isobutyl alcohol, isopropyl carbinol 178-83-1] FEMA 2179... 

Synonyms 2-methyl-1-propanal isobutanol isopropyl carbinol... 

Also known as 2-methyl- 1-propanol and isopropyl carbinol. 

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