Isopropyl methyl ketone

Methyl isopropyl ketone (MIPK) is used as a solvent for lacquers. 

Flammable liquid flash point (closed cup) 7°C (45°F) vapor density 3 (air = 1) vapor pressure 27 torr at 20°C (68°F) vapor can travel some distance to nearby ignition source and flash back fire-extinguishing agent dry chemical, alcohol foam, or CO2 a water spray can be used in diluting and flushing the spill away from exposure. MIPK forms an explosive mixture with air within the range 1.6-8.2% by volume in air. 

MIPK is burned in a chemical incinerator equipped with an afterburner and scrubber. 

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Methyl Isopropyl Ketone. Methyl isopropyl ketone [563-80-4] (3-methyl-2-butanone) is a colorless Hquid with a characteristic odor of lower ketones. It can be produced by hydrating isoprene over an acidic catalyst at 200—300°C (150,151) or by acid-catalyzed condensation of methyl ethyl ketone and formaldehyde to 2-methyl-l-buten-3-one, foUowed by hydrogenation to the product (152). Other patented preparations are known (155,156). Methyl isopropyl ketone is used as an intermediate in the production of pharmaceuticals and fragrances (see Perfumes), and as a solvent (157). It is domestically available from Eastman (Longview, Texas) (47). 

Eigure 2 iHustrates the situation for the system methyl ethyl ketone (MEIQ, methyl isopropyl ketone (MIPK), and water, and the problem of recovering a pure MIPK product from such mixtures. The bow-tie approximation of reachable compositions for several feeds is shown in Eigure 2a the exact reachable compositions are shown in Eigure 2b. 

Fig. 2. Methyl ethyl ketone (MEK)—methyl isopropyl ketone (MIPK)—water system where A1 and A2 represent two different a2eotropes FI, F2, and F3, different feed compositions and Y)n the corresponding bottoms and distillates, respectively (—), the distillation boundary and (B), the reachable compositions for the various feeds (a) approximate bow-tie and (b) exact reachable compositions.

Chemically, wood tar is a complex mixture that contains at least 200 individual compounds, among which the foUowing have been isolated (1) 2-methoxyphenol, 2-methoxy-4-ethylphenol, 5-meth5i-2-methoxyphenol, 2,6-x5ienol, butyric acid, crotonic acid, 1-hydroxy-2-propanone, butyrolactone, 2-methyl-3-hydroxy-4JT-pyran-4-one, 2-methyl-2-propenal, methyl ethyl ketone, methyl isopropyl ketone, methyl furyl ketone, and 2-hydroxy-3-methyl-2-cyclopenten-l-one. 

Chloro methane Methyl chloride 191 CH4CI Methyl isopropyl ketone 126 CsHioO... 

Methyl isopropyl ketone CsHioO 563804 86.1.34 1.8.361E-I-05 -2.6885E-I-02... 

Methyl-2-butanone (methyl isopropyl ketone) [563-80-4] M 86.1, b 93-94 /752mm, d 0.818, n 1.410, pK -7.1 (aq H2SO4). Refluxed with a little KMn04. Fractionated on a spinning-band column, dried with CaS04 and distd. 

Morpholine enamine of methyl isopropyl ketone prepared by this method was found to be a 3 7 mixture of di- and tetrasubstituted isomers (126 and 127). 

Paulsen and Huck also used gas-phase chlorination of ammonia. The mixture, diluted with nitrogen, was led into excess liquid ketone. Diaziridines were obtained from methyl ethyl ketone, diethyl ketone, methyl propyl ketone, and methyl isopropyl ketone. The yields of the crude diaziridines, calculated on the chlorine, were over 90% (Table IV). 

Methyl isoamyl ketone Methyl tsobutyl carbinol Methyl isobutyl ketone Methyl isocyanate Methyl Isopropyl ketone... 

Detectability may be a significant problem with homologous series of unsaturated compounds, particularly //-alkanes. For these compounds, refractive index detection or evaporative light-scattering, both of which are described elsewhere in the book, may be of use. Indirect photometry is a useful detection scheme for compounds that do not absorb in the UV. Acetone, methylethyl ketone, methyl propyl ketone, methyl isopropyl ketone, methyl isobutyl ketone, and acetophenone are added to an acetonitrile/water mobile phase, generating a negative vacancy peak when the nonchro-mophoric analyte emerges and a positive peak if the ketone is adsorbed and displaced.70 Dodecyl, tetradecyl, cetyl, and stearyl alcohols also have been derivatized with 2-(4-carboxyphenyl)-5,6-dimethylbenzimidazole and the derivatives separated on Zorbax ODS in a mobile phase of methanol and 2-propanol.71... 

METHYL-1-BUTENE VALERALDEHYDE METHYL N-PROPYL KETONE METHYL ISOPROPYL KETONE DIETHYL KETONE... 

For those aldehydes and ketones which are volatile enough, gas chromatography of the headspace gases can be used, and this has been used to measure acetone, butyraldehyde, and 2-butanone in oceanic waters. In a gas chromatography-mass spectrometry analysis of a single sample of volatile materials concentrated from inshore waters onto Tenax GC, MacKinnon [ 139] reported tentative identification of methyl isopropyl ketone, bromoform, 4-methyl-2-pentanone, 2-hexanone, and 2-hexanal. 

Methylisopropylbenzene. See Cymene Methyl isopropyl ketone (MIPK), 14 584 in MEK-MIPK-water system, 22 304-305, 306, 307 Methylisoquinolines, 21 205 Methylisothiazolinone, antimicrobial used in cosmetics, 7 831t... 

The procedure worked also with 1,3-octadiene and with isoprene which produced methyl isopropyl ketone in 80-85% yield. 

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