Irritant Skin irritation

Health and Safety Factors (Toxicology). No special precautions are necessary in the handling of malonic acid beyond normal safe handling measures. Due to its acidity malonic acid is classified as a mild irritant (skin irritation, rabbits). The LD q value (oral, rats) for malonic acid is 2750 mg/kg. Transport classification RID/ADR, IMDG-Code, lATA/lCAO not restricted. [Pg.466]

Health and Safety Factors. Handling of cyanoacetic acid and cyanoacetates do not present any specific danger or health hazard if handled with the usual precautions. Cyanoacetic acid is classified as a moderate irritant (skin irritation, rabbits) and has an LD q (oral, rats) of 1500 mg/kg. Methyl and ethyl cyanoacetate are both classified as slight irritants (skin irritation, rabbits) and have an LD q (oral, rats) of 3062 and 2820 mg/kg, respectively. Transport classification cyanoacetic acid RID/ADR 8 IMDG-Code 8 lATA/ICAO 6.1. Methyl and ethyl cyanoacetate RID/ADR 6.1 IMDG-Code 6.1 lATA/ICAO 6.1. [Pg.471]

Health and Safety Factors. Malononitrile is usually available as a soHdifted melt in plastic-Hned dmms. Remelting has to be done carefully because spontaneous decomposition can occur at elevated temperatures, particularly above 100°C, in the presence of impurities such as alkaHes, ammonium, and 2inc salts. Melting should be carried out by means of a water bath and only shordy before use. Occupational exposure to malononitrile mainly occurs by inhalation of vapors and absorption through the skin. Malononitrile has a recommended workplace exposure limit of 8 mg/m, an LD q (oral, rats) of 13.9 mg/kg, and is classified as slight irritant (skin irritation, rabbits). Transport classification RID/ADR 61, IMDG-Code 6.1, lATA/ICAO 6.1. [Pg.474]

Hautreiz, m. skin irritant skin irritation, hautreizend, a. irritating to the skin. Haut-salbe, /. sebaceous matter akin ointment. -substanz,/. hide substance, -talg. m. sebaceous matter,... [Pg.208]

Causes severe eye irritation, skin irritation, nausea, headache, and vomiting. Inhalation is irritating to the mucous membranes and upper respiratory tract. May cause sensitization by skin contact. [Pg.44]

Toxicology category Signal word Oral LDS0 (mg/kg) Dermal LDS0 (mg/kg) Inhalation LCin (mg/L) Eye irritation Skin irritation... [Pg.388]

Triazine technical" Eye irritation Skin irritation Oral LDS0 mg/kg Dermal LDS0 mg/kg Inhalation LCS mg/L Signal word... [Pg.389]

Exposure to glass fibers sometimes causes irritation of the skin and, less frequently, irritation of the eyes, nose, or throat. This is not an allergic reaction, but simply a mechanical irritation. Skin irritation typically is experienced by individuals who are newly exposed to fibrous glass and it usually diminishes after several days of exposure. Good personal and industrial hygiene practices minimize the amount of discomfort experienced. [Pg.665]

Acetone is considered moderately toxic, and is a skin irritant and severe eye irritant. Skin irritation has been reported due to its defatting action, and prolonged inhalation may result in headaches. Inhalation of acetone can produce systemic effects such as conjunctival irritation, respiratory system effects, nausea, and vomiting. ... [Pg.8]

Long-term exposure to 2,4-D has been reported to cause liver, kidney, digestive, muscular, or nervous system damage. Symptoms may include weakness, fatigue, headache, dizziness, loss of appetite, nausea, eye and nasal irritation, skin irritation, hypertension, and slowed heart rate. [Pg.722]

Compound Eye irritation Skin irritation Oral LDgo (9 kg ... [Pg.1503]

Skin or eye surface contact may result in naphthalene cataracts, ocular irritation, skin irritation, and in the case of a sensitized person, severe dermatitis. Topical lesions will clear spontaneously, as soon as the exposure is terminated. [Pg.1770]

Cationic fabric softeners are practically nontoxic by oral or dermal administration [3], Consumers with sensitive skin may suspect softener-treated fabrics to possibly cause adverse effects. Textiles in contact with the skin can have dermatological effects such as allergic reactions and irritations. Skin irritation, however, depends on many parameters such as textile properties, skin sensitivity, and conditions of exposure (e.g., duration, perspiration, and environmental conditions such as climate) [80],... [Pg.521]

HEALTH SYMPTOMS inhalation (headache, vomiting, nausea, abdominal pain) skin absorption (pulmonary damage, central nervous system damage) contact (eye irritation, skin irritation, vesiculation). [Pg.135]

Toxicology Dust may cause none to si. eye irritation, skin irritation TSCA listed... [Pg.47]

Toxicology Severe eye irritant skin irritant, prolonged contact may cause burns ing. may cause nausea, vomiting, and ab minal pain inh. may cause headache and nausea contains DEA LD50 (oral, rat) 710 mg/kg Precaution Incompat. with strong oxidizers Hazardous Ingredierns DEA (5-9%)... [Pg.242]

Toxicoiogy May cause eye irritation, skin irritation on prolong repeated contact inh. of mist may cause eye and respiratory tract inritation, nausea, headache... [Pg.381]

Toxicology LD50 (oral, rat) > 15,380 mg/kg may cause eye irritation, skin irritation on prolonged/repeated contact inh. vapors may cause eye and respiratory tract irritation, nausea, headache Environmental LC50 (rainbow trout, 96 h) 1295 mg/l (daphnia, 48 h) 1660 mg/l relatively nontoxic... [Pg.381]

Regulatory DOT nonregulated SARA 311/312/313 nonreportable Properties Wh. powd. < 5 p particle size char, odor insol. in water vapor pressure < 0.001 mm Hg m.p. 254 C b.p. > 400 C flash pt. (COC) > 265 C pH 8-10 > 99% act. 15.67% P, 27% N Toxicology May cause mild to mod. eye irritation, skin irritation, esp. on prolonged contact, Gl irritation, nausea, vomiting, diarrhea TSCAlisted Precaution Prod, sinks in water strong alkalis may cause hydrolysis Hazardous Decomp. Prods. PO NO, CO, combustion in presence of other materials may release PO NO, CO,... [Pg.892]

Eye Irritation Skin Irritation Skin Sensitization Inhalation ALC... [Pg.200]

Toxicology Primary irritant skin irritant TSCA listed... [Pg.609]

Toxicology LD50 (oral, rat) 3730 mg/kg, (skin, rabbit) 14,100 mg/kg mod. toxic by ing. mildly toxic by skin contact primary irritant skin irritant may cause symptoms of alcohol intoxication on ing. (vomiting, cyanosis, headache, rapid heart rate, low blood pressure, unconsciousness) may affect kidneys low acute toxicity by inh. nonirritating, but can be absorbed thru skin TSCA listed Precaution Combustible liq. avoid contact with acid... [Pg.1311]

Properties Colorless liq. fruity apple-like odor sol. in alcohol insol. in water m.w. 170.25 dens. 0.874 flash pt. (CC) 160 F ref. index 1.424 Toxicology LD50 (oral, rat) > 5 g/kg, (skin, rabbit) > 5 g/kg primary irritant skin irritant TSCA listed... [Pg.2028]

Toxicology LD50 (oral, rat) 7070 mg/kg, (IP, rat) 654 mg/kg, (skin, rabbit) 890 mg/kg LCLo (inh., rat, 4 h) 2000 ppm mod. toxic by skin contact, IP routes mildly toxic by inh., ing. primary irritant skin irritant may cause sensitization by skin contact corrosive TSCA listed Precaution DOT Flamm. liq. flamm. exposed to heat or flame can react vigorously with oxidizers... [Pg.2198]

Toxicoiogy LD50 (oral, rat) 5170 mg/kg, (intramuscular, mouse) 2000 mg/kg mod. toxic by intramuscular route harmful by ing. may be harmful by inh., skin absorp. vapor/mist may cause eye/mucous membrane/upper respiratory tract irritation skin irritant can be a sensitizer TSCA listed Environmentai VOC ThOD 1.97 Precaution Combustible incompat. with strong oxidizing agents, acid chlorides, acid anhydrides... [Pg.4338]

LC50 on inhalation Severe eye irritant skin irritant not a sensitiser. [Pg.619]

Eyes Irritant. Skin Irritant. Respiratory None identified. [Pg.105]

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