Intraductal papillary mucinous neoplasms

FIGURE 15.11 Intraductal papillary mucinous neoplasm with gas-tric/foveolar type papillae is usually negative for MUC1 (left). MUC2 expression is only focal, marking goblet cells (right). 

Immunohistogram of Intraductal Papillary Mucinous Neoplasm with Selected Antibodies... 

Luttges J, Zamboni G, Longnecker D, Kloppel G. The immunohistochemical mucin expression pattern distinguishes different types of intraductal papillary mucinous neoplasms of the pancreas and determines their relationship to mucinous noncys-tic carcinoma and ductal adenocarcinoma. Am J Surg Pathol. 2001 25 942-948. 

Hruban RH, Takaori K, Klimstra DS, et al. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol. 2004 28 977-987. 

Terada T, Ohta T, Kitamura Y, et al. Gell proliferative activity in intraductal papillary-mucinous neoplasms and invasive ductal adenocarcinomas of the pancreas an immunohistochemical study. Arch Pathol Lab Med. 1998 122 42-46. 

Adsay NV, Merati K, Basturk O, et al. Pathologically and biologically distinct types of epithelium in intraductal papillary mucinous neoplasms delineation of an intestinal pathway of carcinogenesis in the pancreas. Am J Surg Pathol. 2004 28 839-848. 

Paal E, Thompson LD, Przygodzki RM, et al. A clinicopatho-logic and immunohistochemical study of 22 intraductal papillary mucinous neoplasms of the pancreas, with a review of the literature. Mod Pathol. 1999 12 518-528. 

Terada T, Ohta T, Nakanuma Y. Expression of oncogene products, anti-oncogene products and oncofetal antigens in intraductal papillary-mucinous neoplasm of the pancreas. His-topathology. 1996 29 355-361. 

Nagai E, Ueki T, Chijiiwa K, et al. Intraductal papillary mucinous neoplasms of the pancreas associated with so-called mucinous ductal ectasia. Histochemical and immunohistochemical analysis of 29 cases. Am J Surg Pathol. 1995 19 576-589. 

Tobi M, Hatfield J, Adsay V, et al. Prognostic Significance of the Labeling of Adnab-9 in Pancreatic Intraductal Papillary Mucinous Neoplasms. Int J Gastrointest Cancer. 2001 29 141-150. 

Fuji H, Inagaki M, Kasai S, et al. Genetic progression and heterogeneity in intraductal papillary-mucinous neoplasms of the pancreas. Am Pathol. 1997 151 1447-1454. 

Nakata B, Yashiro M, Nishioka N, et al. Very low incidence of microsatellite instability in intraductal papillary-mucinous neoplasm of the pancreas. Int J Cancer. 2002 102 655-659. 

Hong SP, Lee EK, Park JY, et al. Cripto-1 overexpression is involved in the tumorigenesis of gastric-type and pancreatobiliary-type intraductal papillary mucinous neoplasms of the pancreas. Oncol Rep. 2009 21 19-24. 

Stukavec J, Jirasek T, Mandys V, et al. Poorly differentiated endocrine carcinoma and intraductal papillary-mucinous neoplasm of the pancreas description of an unusual case. Pathol Res Pract. 2007 203 879-884. 

CT pancreatography is, in substance, the application of virtual endoscopy to the pancreatic gland, allowing the study the inner surface of the gland ducts and resulting useful in evaluating many ductal diseases and, overall, in case of cystic pancreatic neoplasms, especially intraductal papillary mucinous neoplasms (IPMN). 

Even if cystic pancreatic neoplasms account for a very small percentage of the gland tumours, the possibility of some of them to change into malignant lesions determines the necessity to study and stage accurately them and especially mucinous neoplasms and intraductal papillary mucinous neoplasms (IPMN) in both its variants (main and branch duct type) (ITAY et al. 2001). 

Rubin GD, Dake MD, Semba CP et al (1995) Current status of three dimensional spiral CT scanning for imaging the vasculature. Radiol Clin North Am 33 51-70 Sahani DV, Kadavigere R, Blake M et al (2006) Intraductal papillary mucinous neoplasms of pancreas multi detector row CT with 2D curved reformations-Correlations with MRCP. Radiology 238 560-569 Sata N, Kurihara K et al (2006) CT virtual pancreatoscopy a new method for diagnosing intraductal papillary mucinous neoplasm (IPMN) of the pancreas. Abdom Imaging 31 326-331... 

CISS constructive interference steady state IPMN intraductal papillary mucinous neoplasm... 

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