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Interferon gamma lb

Interferon gamma-lb (Imukin ) is used to reduce the incidence of infections in the treatment of chronic granulomatosis. [Pg.411]

Stricter RM, Starko KM, Enelow RI, Noth I, Valentine VG. Effects of interferon-gamma lb on biomarker expression in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2004 170(2) 133-140. [Pg.318]

Raghu, G. et al., A placebo-controlled trial of interferon gamma-lb in patients with idiopathic pulmonary fibrosis, N. Engl. J Med, 350, 125, 2004. [Pg.167]

Toxoplasma gondii, Lelshmania donovani. Listeria monocytogenes, and Mycobacterium avium intracellulare. Interferon gamma-lb was found to enhance osteoclast function in vitro. [Pg.2002]

Dosage form Actimmune is a sterile solution filled in single-dose vials. Each 0.5 ml of Actimmune contains interferon gamma-lb 100 pg. [Pg.198]

Pharmacokinetics According to product label, interferon gamma-lb is rapidly cleared after intravenous administration (1.41iters/min) and slowly absorbed after intramuscular or subcutaneous injection. After intramuscular or subcutaneous injection, the apparent fraction of dose absorbed was greater than 90%. The mean elimination half-life after intravenous administration in healthy male subjects was 38 minutes. The mean elimination half-lives after intramuscular or subcutaneous dosing were 2.9 and 5.9 hours, respectively. Pharmacokinetic studies in patients with chronic granulomatous disease have not been performed. [Pg.199]

H. Other considerations Interferon gamma-lb has been designated an orphan product for use in the treatment of chronic granulomatous disease, renal cell carcinoma, and severe congenital osteoporosis. [Pg.199]

Interferons and cytokines Interferon gamma-lb, human recombinant produced in K coli Actimmune 100 ng 0.5 ml vial (30 MlU/mg) SC... [Pg.462]

Interferon gamma-lb, human recombinant produced in E. coli... [Pg.516]

Interferon gamma-lb [USAN BAN INN] 1-139-Interferon gamma (human lymphocyte protein moiety reduced), N (sup2)-L-methionyl-[CAS gamma is Greek letter] Immukine [TR in UK]... [Pg.516]

AccessMedicine Print Chapter 55. Immunopharmacology Parenteral 0.3 mg powder for SC injection Interferon gamma-lb (Actimmune)... [Pg.1207]

Actimmunc (Interferon gamma-lb) approved for treatment of chronic granulomatous disease. [Pg.214]

Recombinant derived interferon gamma-lb (type 2 interferon)... [Pg.441]

Human recombinant interferon gamma-lb multiple targets within the lymphokine regulatory network... [Pg.932]

Interferons interferon alpha-nl, interferon alpha-n3, interferon alpha-2a, peg interferon alfa-2b, interferon alfacon-1, Interferon alpha-2b, interferon beta-lb, interferon gamma-lb,... [Pg.36]

Todd PA, Goa KL. Interferon gamma-lb. A review of its pharmacology and therapeutic potential in chronic granulomatous disease. Drugs 1992 43(l) lll-22. [Pg.711]

Actimmune Interferon gamma-lb Chronic granulomatous disease... [Pg.288]

Interferon gamma-lb Actimmune (Genentech) Chronic granulomatous disease osteopetrosis... [Pg.271]

Recombinant interferon gamma-lb (rlFN gamma-lb Actimmune)... [Pg.1841]

Interferon Gamma-lb (Recombinant). Interferon gamma-lb, Actimmune. is a recombinant protein expres.sed... [Pg.182]

Interferon gamma-lb is supplied as a solution in sterile water for injection. The. solution must be stored at 2 to 8°C, without freezing. The product cannot tolerate more than 12 hours at room temperature. [Pg.182]

Interferon gamma-lb is a single-chain polypeptide containing 140 amino acids consisting of noncovalent dimers of two identical 16,465-Da monomers. [Pg.343]

Answer C. Interferon-gamma lb (recombinant form) is used in chronic granulomatous disease to decrease infection liability because it increases the formation of tumor necrosis factor (TNF). Infliximab is a monoclonal antibody to TNF used in rheumatoid arthritis, and its use may lead to an increased infection rate. Aldesleukin is a recombinant form of IL-2. [Pg.307]

USA interferon, gamma-lb interferon Actimmune Immukin, Imukin 1 Natural sourced Immuno- stimulant... [Pg.471]

AnsC Interferon-gamma lb (recombinant form) is used in chronic... [Pg.600]

See other pages where Interferon gamma lb is mentioned: [Pg.120]    [Pg.590]    [Pg.618]    [Pg.239]    [Pg.592]    [Pg.198]    [Pg.199]    [Pg.516]    [Pg.516]    [Pg.932]    [Pg.1838]    [Pg.1839]    [Pg.182]    [Pg.155]    [Pg.331]    [Pg.691]    [Pg.357]   
See also in sourсe #XX -- [ Pg.348 ]



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