Inhibitor monitoring and control

Today there are alternatives to the after-the-fact method of inhibitor monitoring and control, with the advent of automatic, semicontinuous, and continuous control methods that employ tagging and tracing and similar techniques. These newer methods can often be linked to computer data management programs. 

Also, it seems to be that, in whatever country considered, the standard method for inhibitor dosing and control tends to be upgraded every 4 to 5 years, with real-time monitoring, microprocessor-controlled systems now leading the way. 

Even the most modem, microprocessor-based monitoring and control systems reference only the primary chemical inhibitor with any real degree of accuracy. Methods for the monitoring and control of secondary inhibitors (such as specific polymeric dispersants) and biodispersants, biocides, antifoams, mud treatments, etc. remain imprecise to say the least. 

The formed plates are washed with water to remove the H2SO4 and are then immersed in a solution containing a suitable oxidation inhibitor for about an hour. Then the plates are dried at a high temperature. Thanks to the technological simplicity and the favourable cost parameters of this drying method, it has found fairly wide application in the battery industry. The main process parameters that need to be monitored and controlled are the drying... 

Monitoring and control of processes are becoming increasingly important in the agricultural, pharmaceutical, textile, food and other industries (1, 16). For animal cell cultures, it is necessary to properly control the feeding of nutrients, removal of products and accumulation of by-product inhibitors in order to increase efficiency and reduce the cost of production (2-6). 

Most of the reported in vivo data presented in the literature involves the infection of donor mice with a strain of P. berghe [61]. After a parasitemia of circa 30% is achieved in the donor mice, a blood sample is taken, diluted, and injected into experimental and control mice. The parasitemia load is regularly monitored for 3 to 7 days after infection by blood smear analysis as a function of drug dose. While in vivo efficacy assays reveal the true scope of a potential antimalarial s efficacy, the methods are very expensive. Consequently, additional assays have been developed to rapidly assess the effectiveness of lead heme aggregation inhibitors. 

Inhibitor monitoring, including operational analysis and control work... 

A PF3 indirect assay using a synthetic substrate was developed in 1979 by Sandberg and Anderson (S2). This test monitored thrombin production with the substrate S-2238 and claimed to be 10 times more sensitive than the above assay and to be free of EDTA interference. Later Harsialvi and coworkers claimed to improve the technique by adding soybean trypsin inhibitor to better control the reaction (H2). These workers believe this assay can be used for diagnosis of platelet disorders. 

If materials selection depends on corrosion control by process-related measures (such as chemical treatment), these should be indicated on the MSD. Indicate the intended injection points and the type of chemical to be injected. Examples include corrosion inhibitors, scale inhibitors, biocides, pH control chemicals, wash water, etc. Also indicate the location of proposed corrosion monitoring and sampling sites. If anodic or cathodic protection is to be part of the corrosion control design, the MSD or its Notes section should indicate the piping and/or equipment to be protected. 

We need more information on the performance of inhibitors, particularly well controlled field trials, and long-term corrosion monitoring. 

Eor most polymer applications the removal of the inhibitors from the monomer is unnecessary. Should it be requited, the phenolic inhibitors can be removed by an alkaline wash or by treatment with a suitable ion-exchange resia. Uninhibited MMA is sufftcientiy stable to be shipped under carehiUy controlled temperature and time restrictions. Uninhibited monomers should be monitored carehiUy and used promptiy. 

Monitor stock, e.g. temperature, pressure, reaction, inhibitor content, degradation of substance, deterioration of packaging or containers/corrosion, leakages, condition of label, expiry date, undesirable by-products (e.g. peroxides in ethers) Spillage control bund, spray, blanket, containment. Drain to collection pit Decontamination and first-aid provisions, e.g. neutralize/destroy, fire-fighting Contain/vent pressure generated to a safe area... 

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