INDEX prostate

An association between meat use and fatal prostate cancer is evident in Table II, although it is not statistically significant. Additional analyses (not shown on table) show a similar degree of association between use of other animal products (eggs, milk, cheese) and fatal prostate cancer. If use of all four animal products are combined into an index which reflects their combined use, a very clear relationship emerges (Table III). Thus, it appears that heavy use of all four animal products is associated with a three-fold increase in risk of fatal prostate cancer. 

Category III prostatitis/chronic pelvic pain syndrome. Extract, administered to men 24 to 58 years old (mean age 43.2), diagnosed with category III prostatitis (CP)/ chronic pelvic pain syndrome (CPPS), at a dose of 325 mg daily for 1 year, produced no appreciable long-term improvement. There was a decrease of mean total National Institutes of Health Chronic Prostatitis Symptom Index score from from 24.7 to 24.6 in the saw palmetto arm (p = 0.41). There were three cases of headache in the saw palmetto group. At the end of the trial, 13 of 32... 

Estimates from multiple logistic regression models including terms for age, study center, education, body mass index, family history of prostate cancer, and total energy intake. b Reference category. 

Pinter O, Molnar J, Toth C, et al. Administration of estramustine in response to changes in the prostate-specific antigen and Karnofsky index in the treatment of prostate cancer. In Vivo. 2005 19 ... 

The most important function of the 4,5-double bond seems to be the protection of the 3-carbonyl function against metabolic inactivation. It is known that 5a-dihydrotestosterone is a more powerful androgen than testosterone, especially when measured by the ventral prostate index. 

I7(x-Methyl-17 -hydroxy-estra-4,9,l l-trien-3-one (Methyltrienolone, N-99). In the course of a steroid total synthesis [293] this compound (Methyltrienolone, N-99) was prepared it was reported [55] to possess 6000% of the androgenic (ventral prostate index), 7500% of the androgenic (seminal vesicles index), and 12,000% of the anabolic (levator ani index) activity of methyltestosterone. Later the anabolic activity was reported [74] to be 30,000% of that of methyltestosterone. As measured by multiple parameters methyltrienolone turned out to be the most hepatotoxic steroid, causing biochemical symptoms of intrahepatic cholestasis [75]. It was also reported [74] to reduce the excretion of 17-ketosteroids and 17-hydroxycorticosteroids and to cause enhancement of the blood coagulation factors V, VII, and X. It also increases the prothrombin content of the plasma [74]. 

Partin, A. W., Mohler, J. L. and Coffey, D. S. (1992). Cell motility as an index of metastatic ability in prostate cancers results with an animal model and with human cancer cells. In Therapy for Genitourinary Cancer (Lepor, H. and Lawson, R. K., eds.). Kluwer Academic Publishers, Dordrecht, pp. 121-130. 

B22. Bodansky, O., Serum phosphohexose isomerase in cancer. III. As an index of tumor growth in metastatic carcinoma of the prostate. Cancer 8, 1087-1114 (1955). 

In a rabbit study, hydroquinone at 150 mg kg day produced minimal developmental alterations in the presence of maternal toxicity. The no-observed-effect level for developmental toxicity was 75mgkg day In rat studies, maternal toxic effects from exposure to hydroquinone included changes in the ovaries, fallopian tubes, and menstrual cycle. Postimplantation mortality was also observed in rat studies. Observed paternal toxic effects from exposure to hydroquinone included changes in the testes, epididymis, sperm duct, prostate, seminal vesicle, Cowper s gland, accessory glands, and male fertility index. Further, exposure to hydroquinone produced skeletal malformations in chickens and ocular and skeletal malformations in rabbits. Hydroquinone can induce renal tubule adenomas, bladder carcinomas, hepatocellular neoplasms, and mononuclear cell leukemia in experimental animals. 

The ProstAsure index, developed by Zhang, Stamey, and Chan, was designed to increase the sensitivity and specificity of cancer detection, while maintaining a reasonable false positive detection rate. The index is derived firom several values, including age, total PSA, creatine kinase isoenzymes, and prostatic acid phosphatase, which are input... 

Babaian RJ, Fritsche HA, Zhang Z, et al. Evaluation of ProstAsure index in the detection of prostate cancer ... 

---