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Biodegradable IP systems

In 1997, Kim and coworkers first developed biodegradable IP systems using a triblock copolymer of PEG and PLLA, PEG-b-PLLA-b-PEG, and demonstrated sustained release of drugs from the hydrogel [127]. After this achievement, many kinds of biodegradable amphiphilic block copolymers (including multiblock copolymers) exhibiting temperature-responsive sol-gel transition have been reported [137, 308-318]. In this review, only several recent results are introduced. [Pg.101]

In this chapter, biodegradable IP systems that can form hydrogels after injection into the body are introduced. Especially, recent progress in biodegradable copolymer systems exhibiting temperature-responsive sol-gel transition (thermogelling polymer) is mainly introduced from the viewpoint of polymer nanoarchitectonics. [Pg.42]

Labow RS, Meek E, Santerre IP. The biodegradation of poly(urethane)s by the estero-lytic activity of serine proteases and oxidative enzyme systems. 1 Biomater Sci Polym Ed 1999 10(7) 699-713. [Pg.105]

See other pages where Biodegradable IP systems is mentioned: [Pg.101]    [Pg.46]    [Pg.55]    [Pg.101]    [Pg.46]    [Pg.55]    [Pg.100]    [Pg.102]    [Pg.1531]    [Pg.41]    [Pg.50]    [Pg.51]    [Pg.101]    [Pg.263]    [Pg.47]   
See also in sourсe #XX -- [ Pg.42 ]



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Biodegradable system

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