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Malignant glioma

Birnbaum T, Roider J, Schankin CJ, Padovan CS, Schichor C, Goldbrunner R, Straube A (2007) Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines. J Neurooncol 83 241-247... [Pg.266]

Pollack IF, DaRosso RC, Robertson PL, Jakacki RL, Mirro JR, Blatt J, Nicholson S, Packer RJ, Allen JC, Cisneros A, Jordan VC (1997) A phase I study of high-dose tamoxifen for the treatment of refractory malignant gliomas of childhood. Clin Cancer Res 3 1109-1115... [Pg.113]

Chen TC,SuS, FryD,Liebes L (2003) Combination therapy with irinotecan and protein kinase C inhibitors in malignant glioma. Cancer 97 2363-2373... [Pg.114]

Zhang W, Law RE, Hinton DR, Couldwell WT. (1997). Inhibition of human malignant glioma cell motility and invasion in vitro by hypericin, a potent protein kinase C inhibitor. Cancer Lett. 120(1) 31-8. [Pg.518]

Wick, W., Fumar, F.B., Naumann. U., Cavenee, W.K., Weller, M. 1999, PTEN gene transfer in human malignant glioma sensitization to irradiation and CD95L-induced apoptosis. Oncogene 18 3936-3943. [Pg.333]

Fitzgerald DJ, Anderson JN (1999) Selective nucleosome disruption by drugs that bind in the minor groove of DNA. J Biol Chem 274(38) 27128-27138 Fox KR, Cons BM (1993) Interaction of mithramycin with DNA fragments complexed with nucleosome core particles comparison with distamycin and echinomycin. Biochemistry. 32(28) 7162—7171 Friedman HS, Kerby T, Calvert, H (2000) Temozolomide and treatment of malignant gliomas. CUn Cancer Res 6 2585-2597... [Pg.183]

Maas RM, Reus K, Diesel B, Steudel WI, Feiden W, et al. 2001. Amplification and expression of splice variants of the gene encoding the P450 cytochrome 25-hydroxyvitamin D(3) 1, alpha-hydroxylase (CYP 27BI) in human malignant glioma. Clin Cancer Res 7 868-875. [Pg.86]

Ronquist G, Hugosson R, Sjolander U, Ungerstedt U. 1992. Treatment of malignant glioma by a new therapeutic principle. Acta Neurochir (Wien) 114(1-2) 8-11. [Pg.253]

Couldwell WT, Antel JP, Yong VW (1992) Protein kinase C activity correlates with the growth rate of malignant gliomas Part II. Effects of glioma mitogens and modulators of protein kinase C. Neurosurgery 31 717-724... [Pg.67]

Couldwell WT, Hinton DR, He S, Chen TC, Sebat I, Weiss MH, Law RE (1994) Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines. FEES Lett 345 43-46... [Pg.67]

Forsyth P, Caimcross G, StewartD, Goodyear M, Wainman N, Eisenhauer E. Phase II trial of docetaxel in patients with recurrent malignant glioma a study of the N ational Cancer Institute of Canada Clinical Trials Group. Invest New Drugs 1996 14(2) 203-206. [Pg.88]

Results with Surgery and Radiation Therapy Trials of Chemotherapeutic Agents Recursive Partitioning Analysis Specific Therapy Considerations in non-GBM Malignant Gliomas Radiation Therapy Strategies Novel Chemotherapeutic Agents Future Directions References... [Pg.129]

Chemoradiation Strategies for Patients with Malignant Gliomas... [Pg.131]

Further support for the use of chemotherapy in patients with malignant glioma has been gleaned from meta-analyses. Using the results from 16 randomized clinical trials involving over 3000 patients, Fine et al. compared survival rates of patients who received radiation alone or radiation plus chemotherapy (8). For patients treated on the evaluated trials with radiation only, median survival ranged from 7 to 34 mo, with a median of... [Pg.132]

Several reasons have been cited for the limitations of the use of chemotherapy in the treatment of malignant glioma. Inherent and acquired drug resistance and the lack of good drug penetration through the blood-brain barrier have both been cited as obstacles. Sev-... [Pg.139]

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Chemoradiation Strategies for Patients with Malignant Gliomas

Gliomas

Malignancy

Malignant

Malignant glioma therapy

Malignant glioma treatment

Malignant gliomas chemotherapy

Malignant gliomas radiation therapy

Malignant gliomas surgery

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