Immunosensors nanomaterials

The material is presented in 17 chapters, covering topics such as trends in ion selective electrodes, advances in electrochemical immunosensors, modem glucose biosensors for diabetes management, biosensors based on nanomaterials (e.g. nanotubes or nanocrystals), biosensors for nitric oxide and superoxide, or biosensors for pesticides. 

Electrochemical behavior of nanomaterials as transducer for biosensors, immunosensors and chemical sensors. 

Nanomaterials as signal-generating substances to be used as labels for immunosensors. 

Problems with the use of electrochemical methods arise from attempts to create reliable, convenient and user-friendly non-toxic sensors. New technologies and materials enable the development of new sensors with unique properties, which has become possible, in particular, due to application of nanomaterials as (i) transducers, (ii) catalytic constituent of enzyme-free sensors and (iii) labels for immunosensors. 

Rusling, J. F., Sotzing, G., Papadimitrakopoulos, F. Designing nanomaterials-enhanced electrochemical immunosensors for cancer biomarker proteins, Bioelectrochem. 76, 189-194 (2009)... 

This book provides a comprehensive compilation of seven chapters, with important contributions of several authors. Chapter 1 reviews the recent research in using nanoparticle labels and multiplexed detection in protein immunosensors. This chapter summarizes recent progress in development of ultrasensitive electrochemical devices to measure cancer biomarker proteins, with emphasis on the use of nanoparticles and nanostmctured sensors aimed for use in clinical cancer diagnostics. Based on recent strategies focused on nanomaterials for electrochemical biosensors development. Chap. 2 discusses the development of new... 

As it can be seen, the number of publications is enormous. The aim of this chapter, rather than attempting a systematic review of the field, is to show in a didactic manner the possibilities of electrochemical immunosensing for food analysis. There are some parts that could be found in other chapters of this book, such as, for example, the use of miniaturized electrodes, nanomaterials, or electrochemical techniques. However, a focus on the knowledge required for understanding their application to food analysis is always made, leaving a deeper treatment for those chapters. On the other hand, the reader can find many important references to the field in recent reviews, from the most general to the particular ones. Thus, recent trends in antibody-based sensors [2] (immunosensors) or smart electrochemical biosensors (from advanced materials to ultrasensitive devices)... 

Li, Q., Zeng, L., Wang, J. et al. (2011) Magnetic mesoporous organic-inorganic NiCo204 hybrid nanomaterials for electrochemical immunosensors. Appl. Mater. 

Rusling, J.F. (2012) Nanomaterials-based electrochemical immunosensors for proteins. Chem. Rec., 12, 164-176. 

Ronkainen, N.J., Okon, S.L., 2014. Nanomaterial-based electrochemical immunosensors for clinically significant biomarkers. Materials 7, 4669 709. 

The EIS can provide useful information on the electron transfer resistance of the electrode surface during stepwise immunosensor construction process. The incorporation of nanomaterials and immobihzation of antibody onto the modified electrode surfaces were characterized by Faradaic EIS in the presence of the Fe(CN)6] redox probe. According to the standard complex function representation, impedance (Z) can be presented as the sum as a real (Z ) and an imaginary part (Z") components. The curve of the EIS includes a semicircular part and a linear part. The semicircle... 

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