Immunology acquired response

An aberrant immune response associated with allergy appears to underlie asthma in most children over age 3 years and in most young adults allergy-induced asthma is also known as extrinsic asthma. In contrast, a large number of patients, especially those who acquire asthma as older adults, have no discernible immunological basis for their condition, although airway inflammation remains a characteristic of the disease this type of... 

These mature, but naive T cells exit peripheral blood and seed lymphoid organs in T-cell specific zones to be acquired by adaptive immune responses for elimination of infected or tumor cells, support for humoral immune responses, formation of immunologic memory, prevention of excessive tissue damage, and facilitation of tissue regeneration (see Chapter 12). 

Immunologicals are all medicines which are either allergens defined cis products used to identify or provoke a specific modification to acquire an immunological response to an antiallergic agent, or vaccines, toxins or sera defined as all agents used to provoke an active or passive immunity to diagnose the state of immunity. 

Acquired immunity is antigen dependent and comprises all the specific immunological reactions associated with lymphocytes. In light of the existence of an antigen-specific defense system, a legitimate question arises as to why we have such an elaborate nonspecific immune system. One of the primary reasons may be that an acquired immune response takes time. For example, 5 days are needed to generate a primary antibody response, and the body must rely on the innate immune system to hold the infection in check during this time. As noted previously, acquired immunity can be subdivided into two effector arms, humoral immunity and cell-mediated immunity. The humor (i.e., a bodily fluid) associated with humoral immunity is the secreted form of Ig in the blood. The cells associated with cell-mediated immunity are the various subpopulations of T cells. 

Li J, Helmerhorst EJ, Corley RB, Luus LE, Troxler RF, Oppenheim FG Characterization of the immunologic responses to human in vivo acquired enamel pellicle as a novel means to investigate its composition. Oral Microbiol Immunol 2003 18 183-191. 

L, Ulbrich K. Acquired and specific immunological mechanisms co-responsible for efficacy of polymer-bound drugs. J Cont Rel 2002 78 97-114. 

Plocova, D., Sirova, M., St astny, M., Rozprimova, L., and Ulbrich, K., 2002, Acquired and specific immunological mechanisms co-responsible for efficacy of polymer-bound drugs. J. Control. Rel. 78 97-114. 

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