Tc-IDA Iminodiacetic Acid Derivatives

6-diethylphenylcarbamoylmethyl)-iminodiacetic acid (Etifenin, Ph. Eur.) N-(2,6-dimethylphenylcarbamoylmethyl)-iminodiacetic acid (Lidofenin, USP) N-(2,4,6-trimehtyl-3-bromophenylcarbamoylmethyl)-iminodiacetic acid (Mebrofenin) N-(2,6-diisopropylphenylcarbamoylmethyl)-iminiodiacetic acid (Disofenin) 

Mebrofenin - TCK-22 (CIS Bio) CholeCIS Choletec (Bracco) Bridatec (Sorin) 

The kit contains the lyophilized, sterile ingredients in a multidose vial. Labeling with Tc eluate is carried out under aseptic conditions by adding 1-5 ml of sterile Tc-so-dium pertechnetate to the vial (0.3-1.5 GBq resp., 8.1-40.5 mCi). The reaction is allowed to proceed at room temperature for 15 min. Tc-iminodiacetic acid (IDA) preparations 

Time of Examination. Hepatobiliary scintigraphy is started 5 min after the intravenous injection. Thereafter, scintigrams are taken at 10-min intervals up to 60 min. If the gallbladder is not visualized within 60 min, delayed images up to 4 h after administration of the radiotracer are obtained. 

150 MBq maximum recommended activity 1-2.6 MBq/kg body weight (normal bilirubin level) 

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