Idiopathic interstitial pneumonia classification

Anonymous (2002) American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001. Am J Respir Crit Care Med 165 277-304... 

American Thoracic Sodety/European Respiratory Society. American Thoracic Society/European Respiratory Society Intemational Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. Am J Respir Crit Care Med 2002 165 277 304. 

In 2002, The American Thoracic Society (ATS) and European Respiratory Society (ERS) published a classification schema recognizing seven idiopathic interstitial pneumonias (llPs) (9) (Table 1). These IIPs have disparate clinical expression and prognosis and will be discussed individually. 

Ohtani Y, Saiki S, Kitaichi M, et al. Chronic bird fancier s lung histopathological and clinical correlation. An application of the 2002 ATS/ERS consensus classification of the idiopathic interstitial pneumonias. Thorax 2005 60(8) 665-671. 

Wittram C, Mark EJ, McLoud TC. CT-histologic correlation of the ATS/ERS 2002 classification of idiopathic interstitial pneumonias. Radiographics 2003 23 1057-1071. 

Leslie KO. Historical perspective a pathologic approach to the classification of idiopathic interstitial pneumonias. Chest 2005 128(suppl 1) 513S-519S. 

American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. 

Flaherty KR, Toews GB, Travis WD, et al. Clinical significance of histological classification of idiopathic interstitial pneumonia. Eur Respir J 2002 19(2) 275-283. 

Kim DS, Collard HR, King TE Jr. Classification and natural history of the idiopathic interstitial pneumonias. Proc Am Thorac Soc 2006 3 285-292. 

LIP is part of a spectrum of pulmonary lymphoid proliferations that includes follicular bronchitis/bronchioUtis, NLH, and MALT B-cell lymphoma (4,5). They can be difficult to differentiate from each other (5,6). Indeed, a substantial percentage of the cases that were initially classified by Averill Liebow (3) as LIP were subsequently found to be mucosa-associated lymphoid tissue (MALT) lymphomas. As a result, LIP was excluded from the classification of idiopathic interstitial pneumonias for several decades. Today, it is clear that the majority of patients with LIP have associated immunologic disorders, dysproteinemias or viral infections, so that LIP can be viewed as a morphologic pattern of lung injury that results from multiple causes with varying pathogenetic mechanisms rather than a distinct disease entity (1). However, a few cases of LIP do present as idiopathic disease. LIP therefore is still included in recent classifications of idiopathic interstitial pneumonias (7). 

A. Lessons from the New Classification of Idiopathic Interstitial Pneumonias... 

Demedts M, Costahel U. ATS/ERS international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Eur Respir J 2002 19(5) 794-796. 

ATS/ERS (2002) International Multidiscplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Grit Care Med 165 277-304 Attfield MD, Hodous TK (1992) Pulmonary function of U.S. coal miners related to dust exposure estimates. Am Rev Respir Dis 145 605-609... 

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