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Hazard analysis cost avoidance

The system is classified according to its application area. On the basis of the results of the hazard analysis (Step 2) and specific legal requirements, the safety requirements to the system are specified. For the manufacturer, it is important that the requirements are established as early as possible in the design process, in order to avoid costly rework later in the development. [Pg.244]

Given the above analysis and also the high cost of purchasing relatively small quantities of 5-aminoimidazole-4-carboxamide (XXIII, AIC), we in Chemical Development were given the backing to explore other possibilities and identify a safer, lower-cost route to Temozolomide that would avoid the hazards and preferably require conventional rather than specialist equipment. Another requirement, made necessary by the heavy workload in our New Jersey Chemical Development operation, was that we find an outside partner to carry out the process exploration work with us. [Pg.297]

As seen from Fig. 1/4.3-2, at any point duty-holders need to balance between sacrifices like trouble, time, and cost with additional risk reduction. Duty-holders need to first identify risks to be avoided, then find the cost, effort, and time to be sacrificed and compare with risk reduction involved. Such judgments are done on the basis of nature of hazard, risk involvement, safety measure, and implementation of safety measures. Therefore, it needs significant analysis to determine how to get into the ALARP range, since values are the main prime mover for this principle. [Pg.44]

Remarkable ecotoxic effects caused by the biodegradation of polymers have rarely appeared in all reviewed papers and reports. Fortunately, a generally very small hazard potential could be assumed. An extensive investigation, applied before the market introduction of a newly designed or composed material, may act as a safety net to avoid unwanted negative effects on ecosystems. The additional cost of such analysis is very low compared with the value of environmental damage unexpected metabolites may cause and compared with the probable loss of confidence of the material users and waste treatment plant operators. [Pg.130]


See other pages where Hazard analysis cost avoidance is mentioned: [Pg.103]    [Pg.103]    [Pg.192]    [Pg.393]    [Pg.109]    [Pg.247]    [Pg.109]    [Pg.191]    [Pg.302]    [Pg.722]    [Pg.10]    [Pg.368]    [Pg.313]    [Pg.914]    [Pg.235]    [Pg.124]    [Pg.375]    [Pg.159]    [Pg.962]    [Pg.247]    [Pg.321]   
See also in sourсe #XX -- [ Pg.104 , Pg.105 ]




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