Growth hormone- releasing

Table 3. Effects of Ovine Somatotropin (oST) and Human Growth Hormone-Releasing Factor (hGRF) on Growth and Composition of Gain in Lambs ...

SRIF acts as an excitatory neuromodulator in the CNS inhibiting the release of TRH, corticotropin-releasing hormone (CRH), growth hormone releasing factor (GHRH), and NE. It produces general arousal and hypotension. It inhibits the release of a number of peptides and modulators in the GI tract. 

J (339), a 28-amino acid peptide, is a member of a family of stmctuially related peptides that includes secretin [1393-25-5] (340), growth hormone releasing factor (GRF), and pituitary adenylate cyclase-activating peptide (PACAP) [137061(341) (83). 

Somatostatin [38916-34-6] M 1637.9, [a]p -36 (c 0.57, 1% AcOH). A tetradecapeptide which is purified by gel filtration on Sephadex G-25, eluting with 2N AcOH, and then by liquid partition chromatography on Sepahdex G-25 using n-BuOH-AcOH-H20 (4 1 5) and has Rp= 0.4. It is a brain growth hormone releasing-inhibiting factor which has also been synthesised. [Burgus et al. Proc Natl Acad Sci USA 70 684 1973, Sorantakis and McKinley Biochem Biophys Res Commun 54 234 1973 Hartridt et al. Pharmazie 37 403 1982.]... 

Somatostatin SOM SST14 SST28 Somatotropin release inhibitory factor (SRIF) Growth hormone release-inhibiting factor... 

Somatostatin is a regulatory cyclic peptide, which has originally been described as a hypothalamic growth hormone release-inhibiting factor. It is produced throughout the central nervous system (CNS) as well as in secretoty cells of the periphery and mediates its regulatory functions on cellular processes such as neurotransmission, smooth muscle contraction, secretion and cell proliferation via a family of seven transmembrane domain G-protein-coupled receptors termed sstx 5. 

Growth Hormone Release-inhibiting Factor GSK3... 

Somatostatin Growth hormone-release inhibiting factor (8,9) (51110-01-1)... 

Such difficulties prompted research workers to look for some other index of NT function in humans. These range from studies on platelets, such as abnormalities in their amine uptake and MAO activity in depressed patients, to changes in the secretion of a hormone known to be controlled by a particular NT. Thus if NA controls growth hormone release, and the secretion of the hormone is changed in depressed patients, does that confirm a role for NA in the mediation of depression ... 

G18. Gottardis, M Nigitsch, C., Schmutzhard, E Neumann, M Putensen, C., Hackl, J. M., and Roller, W The secretion of human growth hormone stimulated by human growth hormone releasing factor following severe cranio-cerebral trauma. Intensive Care Med. 16, 163-166... 

Frieboes, R. M., Murck, H., Maier, P. et al. (1995). Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man. Neuroendocrinology 61, 584-9. 

Kojima, M Hosoda, H., Date, Y. et al. (1999). Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-60. 

Moreno-Reyes, R., Kerkhofs, M., LHermite-Baleriaux, M. et al. (1998). Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation. Am. J. Physiol. 274, E779-84. 

CRH corticotropin releasing hormone GHRH growth hormone releasing hormone GnRH gonadotropin releasing hormone Somatostatin... 

Pannell, C., Simonian, S. X., Gillies, G. E., Luscher, B., and Herbison, A. E. (2002) Hypothalamic somatostatin and growth hormone-releasing hormone mRNA expression depend... 

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