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Growth factors glial-derived neurotrophic

Insulin-like growth factor receptor (IGFR) Colony-stimulating factor receptor (CSFR) Nerve growth factor receptor (NGFR) Hepatocyte growth factor receptor (Met) Glial-derived neurotrophic factor receptor (RET)... [Pg.385]

Especially, in vitro studies helped to understand the different ways of induction by astrocytes. These are able to secrete a range of chemical agents including transforming growth factor-P (TGF-P), glial-derived neurotrophic factor (GDNF), basic... [Pg.266]

Role/Function of NGF. NGF is a neurotrophic protein molecule essential for the growth and survival of sympathetic and small-diameter afferent neurons (nociceptors) [27, 28] and is involved in neuronal function and plasticity [24]. NGF belongs to the neurotrophin family, which also includes the brain-derived neurotrophic factor (BDNF), glial-derived neurotrophic factor (GDNF), neurotrophin-3 (NT-3), and neurotrophin 4/5 (NT-4/5) [29, 30]. [Pg.1175]

BDNF, brain derived neurotrophic factor CBF, cerebral blood flow GDNF, glial cell line derived neurotrophic factor NGF, nerve growth factor TfR, transferrin receptor VIP, vasoactive intestinal polypeptide. [Pg.45]

Dozens of neurotrophic factors regulate the survival of neurons in the central and peripheral nervous systems (Table 1—3). A veritable alphabet soup of neurotrophic factors contributes to the brain broth of chemicals that bathe and nourish nerve cells. Some are related to nerve growth factor (NGF), others to glial cell line—derived neurotrophic factor (GDNF) and still others to various other neurotrophic factors (Table 1—3). Some neurotrophic factors can trigger neurons to commit cellular suicide by making them fall on their apoptotic swords. The brain seems to choose which nerves live or die partially by whether a neurotrophic factor nourishes them... [Pg.26]

Currendy, there are six members of the neurotrophin family, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial-cell-line-derived neurotrophic factor, (GDNF), and neurturin , which is structurally related to GDNF," 3 as well as several neurotrophins, NT-3, -4, and -5. [Pg.14]

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Glial

Glial growth factor

Growth factor glial-derived

Neurotrophic

Neurotrophic factors

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