Growth factor glial-derived

Shih, A. and Holland, E. 2006. Platelet-derived growth factor (PDGF) and glial tumorigenesis. Cancer Letters 232(2), 139-147. 

NT3 is also critical for glial development. There is good evidence that NT3 acts to stimulate the proliferation of oligodendrocyte precursor cells, probably in concert with platelet derived growth factor (PDGF) (see below). 

ES cells aggregated into embryoid bodies and propagated in growth factors, including platelet-derived growth factor, differentiate rapidly to include CNS glial cells. 

BDNF, brain derived neurotrophic factor CBF, cerebral blood flow GDNF, glial cell line derived neurotrophic factor NGF, nerve growth factor TfR, transferrin receptor VIP, vasoactive intestinal polypeptide. 

Insulin-like growth factor receptor (IGFR) Colony-stimulating factor receptor (CSFR) Nerve growth factor receptor (NGFR) Hepatocyte growth factor receptor (Met) Glial-derived neurotrophic factor receptor (RET)... 

Dozens of neurotrophic factors regulate the survival of neurons in the central and peripheral nervous systems (Table 1—3). A veritable alphabet soup of neurotrophic factors contributes to the brain broth of chemicals that bathe and nourish nerve cells. Some are related to nerve growth factor (NGF), others to glial cell line—derived neurotrophic factor (GDNF) and still others to various other neurotrophic factors (Table 1—3). Some neurotrophic factors can trigger neurons to commit cellular suicide by making them fall on their apoptotic swords. The brain seems to choose which nerves live or die partially by whether a neurotrophic factor nourishes them... 

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