GOTO cells

Carotenoids have beneficial effects in cancer chemoprevention (Astrog, 1997). Fucoxanthin, one of the the major carotenoids in brown algae, is known to exhibit antitumor activity against human neuroblastoma GOTO cells (Okuzumi et al., 1990). Inhibitory effects on mouse duodenum and on skin carcinogenesis have also been reported (Okuzumi et al., 1993 Satomi et al., 1996). 

Nakayama Y., Miyamura M., Hirano Y., Goto K., Matsuda T., Preparation of poly(ethylene glycol)-polystyrene block copolymers using photochemistry of dithiocarbamate as a reduced cell-adhesive coating material, Biomaterials 1999 20 963-970. 

Ogawa-Goto, K., Tanaka, K., Ueno, T., Tanaka, K., Kurata, T., Sata, T., and Irie, S. (2007) pi80 is involved in the interaction between the endoplasmic reticulum and microtubules through a novel microtubule-binding and bundling domain. Mol. Biol. Cell. 10.1091/mbc.E06-12-1125. 

The bone becomes depleted of calcium salts when the urine is acidic over a relatively long period. This was shown by Goto (17) who fed rabbits large doses of hydrochloric acid. He then showed that urinary calcium loss occurred in concert with a marked reduction in mass of the skeletal system, and also that the total non-fat dry weight of bone decreased,implying a loss of bone matrix. A dose-dependent, dietary acid induced loss of labelled calcium from rat bone has been reported by Thorn and his coworkers (18). They demonstrated that in response to graded doses of ascorbic acid, cells in tissue culture, and bones in whole animals fed such doses were depleted of the labelled calcium. 

Takahashi, K., Y. Sawasaki, J. Hata, K. Mukai, and T. Goto. 1990. Spontaneous transformation and immortalization of human endothelial cells. In Vitro Cell Dev Biol 26(3 Pt 1) 265-74. 

A solution of styrene in methanol to impregnate wood samples, followed by polymerization, was used by Furuno and Goto (1979). Penetration of the monomer into the cell wall was determined by solvent extraction of samples after polymerization. This removed lumen located polymer, whilst leaving the cell wall bound polymer in place. This showed that the concentration of cell wall bound polymer increased in proportion to the monomer content in methanol, up to a maximum of 80% of the monomer in the solvent. No cell wall penetration was observed for treatment with neat monomer. This was also found for bulking of the wood, as determined from external dimensions of the samples. Improvements in ASE were obtained as a result of the presence of cell wall bound polymer. To achieve similar ASE values with lumen located polymer required very high polymer loadings. 

Furuno, T. and Goto, T. (1979). Structure of the interface between wood and synthetic polymer. Xll. Distribution of styrene polymer in the cell wall of wood-polymer composite (WPG) and dimensional stability. Mokuzai Gakkaishi, 25(7), 488 95. 

Ogata Y, Goto H, Kimura T, et al. Development of neo red cells (NRC) with the enzymatic reduction system of methemoglobin. Artif Cells Blood Substit Immobil Biotechnol 1997 25 417. 

M. Yanagisawa, H. Kurihara, S. Kimura, Y. Tomobe, M. Kobayashi, Y. Mitsui, Y. Yazaki, K. Goto, A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332 (1988) 411-415. 

Takahashi, M., Mochizuki, M., V feda, K., Itoh, T., and Goto, M. (1994) Studies on dissolution tests of soft gelatin capsules. Part 5. Rotating dialysis cell metlSHutem. Pharm. Bull., 42 1672-1675. 

H3. Hayashi, J. L., Ohta, S., Kikuchi, A., Takemitsu, M., Goto, Y. I., and Nonaka, I., Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. Proc. Natl. Acad. Sci. USA 88, 10614-10618 (1991). 

Suzuki, H., Kumagai, T., Goto, A., and Sugiura, T., Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells. Biochem. Biophys. Res. Commun. 249, 542-545 (1998). 

Goto, M., Sato, K., Tokeshi, M., Kitamori, T., Development of microchip-based bioassay system using cultured cells. Micro Total Analysis Systems 2003, Proceedings 7th pTAS Symposium, Squaw Valley, CA, Oct. 5-9, 2003, 785-788. 

Yoh K, Ishii G, Yokose T, Minegishi Y, Tsuta K, Goto K, Nishiwaki Y, Kodama T, Suga M, Ochiai A. Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer. Clin Cancer Res 2004 10 1691-1697. 

Tsuji, S., Yamashita, T., Matsuda, Y., and Nagai, Y. (1992). A novel glycosignaling system GQlb-dependent neuritogenesis of human neuroblastoma cell line, GOTO, is closely associated with GQlb-dependent ecto-type protein phosphorylation. Neurochem. Int. 21, 549-554. 

Macros include keystrokes such as RETURN, GOTO, etc. so that the user does not have to carry them out. However, keys such as RETURN, GOTO, DOWN,. .. cannot be entered directly in a cell. For each of these keys, there is a key indicator, e.g. the indicator for RETURN is for GOTO goto, ... etc. 

In this example, the macro first moves the cell pointer to cell AA1 with the goto command. Here the user is asked for how many variables he wants to make the ruggedness (the answer is supposed to be either 3 or 7). Then the macro moves the cell pointer to cell AA2, where the user has to enter his/hers answer, i.e., 3 or 7. 

Maruyama, K., Goto, C., Numata, M., Suzuki, T., Nakagawa, Y., et al., O-acetylated xyloglucan in extracellular polysaccharides from cell-suspension cultures of Mentha. Phytochemistry 1996,41 (5), 1309-14. 

Ohtani N, Goto T, Waeber C, Bhide PG. 2003. Dopamine modulates cell cycle in the lateral ganglionic eminence. J... 

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