Glycoproteins receptor ligands

Wang,K. C.,Koprivica,V.,Kim, J.A etal. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature 417 941-944,2002. 

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Wang, K. C., Koprivica, V., Kim, J. A., Sivasankaran, R., Guo, Y., Neve, R. L., and He, Z. (2002a). Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature 417, 941-944. 

Among the common macromolecules that vertebrate cells internalize by receptor-mediated endocytosis are cholesterol-containing particles called low-density lipoprotein (LDL) the iron-binding protein transferrin many protein hormones (e.g., insulin) and certain glycoproteins. Receptor-mediated endocytosis of such ligands generally occurs via clathrin/AP2-... 

An exception to the general theme of pH-dependent receptor-ligand dissociation in the late endosome occurs in the endocytic pathway that delivers transferrin-bound Iron to cells. A major glycoprotein in the blood, transferrin transports Iron to all tissue cells from the liver (the main site of iron... 

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