Proteins hormones

Drugs can affect thyroid function in a number of ways.41 Effects of drugs on thyroid hormone protein binding, LT4 absorption, and metabolism have been discussed previously. Several commonly used medications can alter thyroid hormone secretion. 

Describe biochemical and functional distinctions among steroid hormones, protein/peptide hormones, and amine hormones... 

Feature Steroid hormones Protein/peptide hormones Amine hormones Thyroid hormones Catecholamines ... 

A dynamic equilibrium exists between the bound and the free fractions hormone-protein complex protein + free hormone... 

Immunoassays have found wide applications in the field of clinical diagnostics for the detection and measurement of drugs, vitamins, hormones, proteins in general, metabolites, microorganisms, and other substances of interest in biological... 

Growth hormone—Protein produced by a small collection of cells in the brain that influences the growth of bones, the production of proteins, and the use... 

While many hormones bind to surface receptors the steroid hormones, which are lipid in nature, pass through the cell membrane and bind to receptor proteins in the nucleus. The resulting hormone-protein complexes induce changes in gene expression through regulation of transcription (Fig. 11-1, top). These receptors are considered in Chapter 22 and hormones are considered further in Chapter 30. 

With the availability of labeled hormones of high specific activity and the application of the principles of affinity chromatography, researchers were able to isolate cellular proteins that bind to plant hormones in vitro. Such proteins have been referred to as receptor proteins, binding proteins, or acceptor proteins. Tacit in the concept of hormone receptor proteins is the stereo-specific interaction of the hormone and the receptor protein (19). The resulting hormone-protein complex participates in growth processes that depend on new or enhanced protein synthesis. Advances in molecular biology and related sciences have enabled many researchers to study the role of receptors in the control of nuclear functions or other activities and to determine the site of primary hormonal action. 

Clinical Science sterones, sterols hormones proteins saccharides... 

Cody, V., and Murray-Rust, P. Iodine- X(0, N, S) intermolecular contacts models of thyroid hormone-protein binding interactions using information from the Cambridge Crystallographic Data Files. J. Molec. Struct. 112, 189-199... 

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